Evidence map›Paper›PMID 29246489›Full record

ArticleNeuropsychologia2018

Post-secondary maternal education buffers against neural risk for psychological vulnerability to future life stress.

Johnna R Swartz, Annchen R Knodt, Spenser R Radtke, Ahmad R Hariri

Abstract read
In one paragraph

Article in Neuropsychologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  5. Understanding societal challenges: a NeurotechFrontiers in neuroscience · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Johnna R SwartzDepartment of Human Ecology, University of California, Davis, 1353 Hart Hall, Davis, CA 95616, USA. Electronic address: jrswartz@ucdavis.edu.
Annchen R KnodtLaboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC 27708, USA.
Spenser R RadtkeLaboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC 27708, USA.
Ahmad R HaririLaboratory of NeuroGenetics, Department of Psychology & Neuroscience, Duke University, Durham, NC 27708, USA.
Duke University · USUniversity of California, Davis · US

Funding

Quantifying Individual Differences in Midlife Structural Brain Integrity Associated with Later AD/ADRD RiskR01AG049789 · NIA · DUKE UNIVERSITY · PI AHMAD R. HARIRI, TERRIE E MOFFITT · 2015 to 2026
$10.6M
Neurogenetic Pathways to Drug Use in Young AdultsR01DA033369 · NIDA · DUKE UNIVERSITY · PI HARIRI, AHMAD R. · 2013 to 2016
$1.4M
NIA NIH HHS R01 AG049789NIDA NIH HHS R01 DA033369
6 · The paper itself

Abstract

We have previously reported that threat-related amygdala activity measured during a baseline fMRI scan predicts the experience of depression and anxiety associated with stressful life events years later. Here, we examine whether two broad measures of childhood environmental enrichment, namely parental educational achievement and subjective parental socioeconomic status, buffer against the effects of amygdala activity on future vulnerability to stress. Analyses of data available from 579 young adults revealed that maternal, but not paternal, educational achievement moderates the association between amygdala activity, recent life stress, and changes in mood and anxiety symptoms, even when controlling for participants' current subjective socioeconomic status. Specifically, only participants reporting lower maternal educational achievement exhibited our previously observed interaction between amygdala activity and future life stress predicting increases in depression and anxiety. These results suggest that higher maternal educational achievement may help buffer stress sensitivity associated with heightened threat-related amygdala activity.

Indexed as

Educational StatusResilience, PsychologicalAdolescentAffectAmygdalaAnxietyDisease SusceptibilityFemaleHumansMaleMothersStress, PsychologicalUniversitiesYoung AdultAmygdalaAnxietyDepressionfMRISocioeconomic statusStress

Identifiers

PMID29246489
PMCPMC5801164
OpenAlexW2771304512

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.