Evidence map›Paper›PMID 29246167›Full record

ArticleBMC oral health2017

The Candida species that are important for the development of atrophic glossitis in xerostomia patients.

Sachika Nakamura, Mariko R Okamoto, Ken Yamamoto, Akihisa Tsurumoto, Yoko Yoshino, Hiroshi Iwabuchi, Ichiro Saito, Nobuko Maeda, Yoichi Nakagawa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sachika NakamuraDepartment of Clinical Pathophysiology., Tsurumi University School of Dental Medicine, Tsurumi University Dental Hospital, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan.
Mariko R OkamotoDepartment of Clinical Pathophysiology., Tsurumi University School of Dental Medicine, Tsurumi University Dental Hospital, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan.
Ken YamamotoDepartment of Clinical Pathophysiology., Tsurumi University School of Dental Medicine, Tsurumi University Dental Hospital, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan.
Akihisa TsurumotoCommunity Dentistry, Tsurumi University School of Dental Medicine, Yokohama, Japan.
Yoko YoshinoDepartment of Clinical Pathophysiology., Tsurumi University School of Dental Medicine, Tsurumi University Dental Hospital, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan.
Hiroshi IwabuchiDepartment of Dentomaxillofacial Diagnosis and Treatment, Division of Oral and Maxillofacial Surgery, Graduate School of Kanagawa Dental University, Yokosuka, Japan.
Ichiro SaitoDepartment of Clinical Pathophysiology., Tsurumi University School of Dental Medicine, Tsurumi University Dental Hospital, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan.
Nobuko MaedaDepartment of Oral Microbiology, Tsurumi University, School of Dental Medicine, Yokohama, Japan.
Yoichi NakagawaDepartment of Clinical Pathophysiology., Tsurumi University School of Dental Medicine, Tsurumi University Dental Hospital, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, 230-8501, Japan. nakagawa-y@tsurumi-u.ac.jp.
Tsurumi University · JPKanagawa Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to clarify the species of Candida that are important for the development of atrophic glossitis in xerostomia patients.

methodsA total of 231 patients with subjective dry mouth were enrolled in the present study. Logistic regression analysis was performed to clarify the contribution of each Candida species and other variables to the development of atrophic glossitis. The dependent variable was the absence/presence of atrophic glossitis. The Candida colony-forming units (CFU) of C. albicans, C. glabrata, C. tropicalis, and C. krusei, as well as age, gender, resting (RSFR) and stimulated (SSFR) whole salivary flow rate, and denture-wearing status, were treated as explanatory variables.

resultsLogistic regression analysis showed that two factors were closely associated with the presence of atrophic glossitis: an increase in C. albicans CFU and a decrease in the SSFR.

conclusionsC. albicans, but not non-albicans Candida, was associated with atrophic glossitis in xerostomia patients who had no systemic predisposing factors, indicating that C. albicans remains a treatment target for Candida-related atrophic glossitis.

Indexed as

AgedAged, 80 and overAtrophyCandidaCandida albicansCandidiasisColony Count, MicrobialFemaleGlossitisHumansLogistic ModelsMaleMiddle AgedTongueXerostomiaAtrophic glossitisCandida speciesCandidiasisLogistic regression analysisXerostomia

Identifiers

PMID29246167
PMCPMC5732471
OpenAlexW2771891040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.