Evidence map›Paper›PMID 29245899›Full record

ArticleOncotarget2017

Constitutive Cyclin O deficiency results in penetrant hydrocephalus, impaired growth and infertility.

Marc Núnez-Ollé, Carole Jung, Berta Terré, Norman A Balsiger, Cristina Plata, Ramon Roset, Carlos Pardo-Pastor, Marta Garrido, Santiago Rojas, Francesc Alameda and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Formation and function of multiciliated cells.The Journal of cell biology · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Development of a multiciliated cell.Current opinion in cell biology · 2022
    Review
  10. Review
  11. Ependymal Cilia: Physiology and Role in Hydrocephalus.Frontiers in molecular neuroscience · 2022
    Review
  12. Article
  13. Semi-Lethal Primary Ciliary Dyskinesia in Rats Lacking theInternational journal of molecular sciences · 2021
    Article
  14. Motile cilia genetics and cell biology: big results from little mice.Cellular and molecular life sciences : CMLS · 2021
    Review
  15. Cyclin-dependent kinases and rare developmental disorders.Orphanet journal of rare diseases · 2020
    Review
  16. Review
  17. Atypical cyclins: the extended family portrait.Cellular and molecular life sciences : CMLS · 2020
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 1 country.

Marc Núnez-OlléApoptosis Signalling Group, IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Barcelona, Spain.
Carole JungLaboratory of Molecular Physiology, Universitat Pompeu Fabra, Barcelona, Spain.
Berta TerréInstitute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology, Barcelona, Spain.
Norman A BalsigerApoptosis Signalling Group, IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Barcelona, Spain.
Cristina PlataLaboratory of Molecular Physiology, Universitat Pompeu Fabra, Barcelona, Spain.
Ramon RosetApoptosis Signalling Group, IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Barcelona, Spain.
Carlos Pardo-PastorLaboratory of Molecular Physiology, Universitat Pompeu Fabra, Barcelona, Spain.
Marta GarridoApoptosis Signalling Group, IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Barcelona, Spain.
Santiago RojasUnit of Human Anatomy and Embryology, Department of Morphological Science, Faculty of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Francesc AlamedaApoptosis Signalling Group, IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Barcelona, Spain.
Josep LloretaServei de Patologia, Hospital del Mar-IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Barcelona, Spain.
Juan Martín-CaballeroParc de Recerca Biomèdica de Barcelona, Barcelona, Spain.
Juana M FloresDepartamento de Medicina y Cirugía Animal, Facultad Veterinaria, Universidad Complutense de Madrid, Madrid, Spain.
Travis H StrackerInstitute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology, Barcelona, Spain.
Miguel A ValverdeLaboratory of Molecular Physiology, Universitat Pompeu Fabra, Barcelona, Spain.
Francisco J MuñozLaboratory of Molecular Physiology, Universitat Pompeu Fabra, Barcelona, Spain.
Gabriel Gil-GómezApoptosis Signalling Group, IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Barcelona, Spain.
Hospital del Mar Research Institute · ESPompeu Fabra University · ESInstitute for Research in Biomedicine · ESBarcelona Biomedical Research Park · ESUniversidad Complutense de Madrid · ESUniversitat Autònoma de Barcelona · ES

Funding

High-throughput targeted mutagenesis of mouse stem cell linesU01HG004080 · NHGRI · CHILDREN'S HOSPITAL & RES CTR AT OAKLAND · PI DE JONG, PIETER J. · 2006 to 2010
$28.1M
Production of Targeted Null Mutations for 10,000 Genes in C57BL/6 ES CellsU01HG004085 · NHGRI · REGENERON PHARMACEUTICALS, INC. · PI VALENZUELA, DAVID MANUEL · 2006 to 2010
$25.3M
UCD KOMP PROJECT REPOSITORYU42RR024244 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LLOYD, KC KENT · 2007 to 2010
$7.9M
NCRR NIH HHS U42 RR024244NHGRI NIH HHS U01 HG004080NHGRI NIH HHS U01 HG004085
6 · The paper itself

Abstract

Cyclin O (encoded by

Indexed as

ciliogenesisCyclin OdevelopmentGerotargethydrocephalusneurogenesis

Identifiers

PMID29245899
PMCPMC5725090
OpenAlexW2763566153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.