SynthesisMedicine2017
Systematic review and meta-analysis to compare success rates of retrograde intrarenal surgery versus percutaneous nephrolithotomy for renal stones >2 cm: An update.
Synthesis in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03924362 (A Prospective Trial of Feasibility and Efficacy of Simultaneous Bilateral Percutaneous Nephrolithotomy), which is not on this map. Cited by 33 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Trial of Feasibility and Efficacy of Simultaneous Bilateral Percutaneous Nephrolithotomy
Who cites it
33 citing papers in PubMed, 5 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Pooled it
- Comparison of safety and efficacy of negative pressure aspiration assisted retrograde intrarenal surgery and traditional percutaneous nephrolithotomy in the treatment of upper urinary tract stones larger than 2 cm: a systematic review and meta-analysis.International journal of surgery (London, England) · 2025Pooled it
- Comparison of suction technique and non-suction technique in retrograde intrarenal stone surgery: a systematic review and meta-analysis.International urology and nephrology · 2025Pooled it
- Is physical therapy effective following extracorporeal shockwave lithotripsy and retrograde intrarenal surgery: a meta-analysis and systematic review.BMC urology · 2020Pooled it
- Comparison of retrograde flexible ureteroscopy and percutaneous nephrolithotomy in treating intermediatesize renal stones (2-3cm): a meta-analysis and systematic review.International braz j urol : official journal of the Brazilian Society of UrologyPooled it
- Use of Novel 6.3 Fr Ureteroscope in Endoscopic Combined Intrarenal Surgery (ECIRS): Comparative Experience with Conventional Ureteroscopes.Journal of clinical medicine · 2026Article
- Development of a machine learning model for predicting urosepsis after ureteroscopic lithotripsy.Urolithiasis · 2026Article
- Intelligent pressure-controlled ureteral access sheath combined with flexible ureteroscopy versus flexible ureteroscopy and percutaneous nephrolithotomy for renal stones less than 3 cm in diameter: a comparative efficacy study.World journal of urology · 2025Article
- Article
- Article
- Relocation and evacuation of stone fragments using 7.5 Fr flexible ureteroscope with direct-in-scope suction: an experimental study.Central European journal of urology · 2025Article
- Clinical advantages of suctioning flexible ureteroscopy with intelligent pressure control on treating large upper urinary tract calculi.Frontiers in surgery · 2025Article
- Laser fibers and baskets. How do they affect suction and intrarenal pressures using the novel single-use flexible direct in-scope suction ureteroscopes?Central European journal of urology · 2025Article
- In the Treatment of Lower Pole Kidney Stones Between 1-2 cm in Children, Which is the Best Approach? Retrograde Intrarenal Surgery or Mini Percutaneous Nephrolithotomy.Sisli Etfal Hastanesi tip bulteni · 2024Article
- Comparative Analysis of Surgical Outcomes of Flexible Ureteroscopy and Da Vinci Robotic Surgery in Community Patients with Renal Pelvic Stones Larger than 2 cm.Medicina (Kaunas, Lithuania) · 2023Article
- Comparison of stone-free rate between percutaneous nephrolithotomy and retrograde intrarenal surgery.Journal of the Chinese Medical Association : JCMA · 2023Article
- Influencing factors of acute kidney injury following retrograde intrarenal surgery.World journal of urology · 2023Article
- Article
- Comparison between Retrograde Flexible Ureteroscopy and Percutaneous Nephrolithotomy for the Treatment of Renal Stones of 2-4 cm.Medicina (Kaunas, Lithuania) · 2023Article
- In Vivo Feasibility Test of a New Flexible Ureteroscopic Robotic System, easyUretero, for Renal Stone Retrieval in a Porcine Model.Yonsei medical journal · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe performed a systematic review and meta-analysis comparing stone-free rates between retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PCNL), using updated, more reliable evidence. MATERIALS AND
methodsRandomized controlled trials comparing RIRS and PCNL for >2 cm stones were identified from electronic databases. Stone-free rates for the procedures were compared by qualitative and quantitative syntheses (meta-analyses). Outcome variables are shown as risk ratios (RRs) with 95% confidence intervals (CIs).
resultsEleven articles were included in this study. Most recently published studies exhibited relatively low quality during quality assessment. For the meta-analysis comparing success (stone-free) rates between PCNL and RIRS, the forest plot using the random-effects model showed an RR of 1.11 (95% CI 1.02-1.21, P < .014) favoring PCNL. After determining the among-study heterogeneity, subgroup analysis was performed of 9 studies with less heterogeneity: the stone-free rate of PCNL was superior to that of RIRS using a fixed-effect model (RR 1.07, 95% CI 1.01-1.14, P < .019) for these studies.
conclusionsRIRS can be a safe and effective procedure for selected patients with large renal stones. However, in this meta-analysis, the postoperative stone-free rate of PCNL was higher than that of RIRS in patients with >2 cm renal stones.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.