Evidence map›Paper›PMID 29245053›Full record

ArticleBiomaterials2018

Influence of diabetes on the foreign body response to nitric oxide-releasing implants.

Robert J Soto, Elizabeth P Merricks, Dwight A Bellinger, Timothy C Nichols, Mark H Schoenfisch

Open access · bronzeAbstract read
In one paragraph

Article in Biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Mechanisms of Foreign Body Response Mitigation by Nitric Oxide Release.International journal of molecular sciences · 2022
    Article
  6. Review
  7. Early administration of L-arginine inFASEB bioAdvances · 2021
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Robert J SotoDepartment of Chemistry, University of North Carolina, Chapel Hill, NC, 27599, United States.
Elizabeth P MerricksDepartments of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, 27599, United States.
Dwight A BellingerDepartments of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, 27599, United States.
Timothy C NicholsDepartments of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, 27599, United States.
Mark H SchoenfischDepartment of Chemistry, University of North Carolina, Chapel Hill, NC, 27599, United States. Electronic address: schoenfisch@unc.edu.
University of North Carolina at Chapel Hill · US

Funding

Role of diabetes and nitric oxide release duration on analytical performance of in vivo glucose biosensorsR01DK108318 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHOENFISCH, MARK H · 2016 to 2023
$4.5M
NIDDK NIH HHS R01 DK108318
6 · The paper itself

Abstract

The foreign body response (FBR) to nitric oxide (NO)-releasing subcutaneous implants was compared between healthy and streptozotocin-induced diabetic swine by evaluating inflammation, collagen capsule formation, and angiogenesis. Steel wire substrates were first modified with polyurethane membranes capable of diverse NO-release kinetics (NO fluxes and release durations of 0.8-630.0 pmol cm

Indexed as

Implants, ExperimentalAnimalsCollagenDiabetes Mellitus, ExperimentalFemaleForeign-Body ReactionInflammationMaleNeovascularization, PathologicNitric OxidePolyurethanesSubcutaneous TissueSwineCollagenNitric OxidePolyurethanesDiabetesForeign body responseGlucose biosensorInflammatory responseNitric oxideWound healing

Identifiers

PMID29245053
PMCPMC6121707
OpenAlexW2771644116

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.