Evidence map›Paper›PMID 29245024›Full record

ArticleAddictive behaviors2018

Early-onset tobacco use and suicide-related behavior - A prospective study from adolescence to young adulthood.

Tellervo Korhonen, Elina Sihvola, Antti Latvala, Danielle M Dick, Lea Pulkkinen, John Nurnberger, Richard J Rose, Jaakko Kaprio

Open access · greenAbstract read
In one paragraph

Article in Addictive behaviors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Self-harming behavior linked to earlier onset of cardiovascular disease in severe mental disorders.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Dual-harm in adolescence and associated clinical and parenting factors.Social psychiatry and psychiatric epidemiology · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. FinnTwin12 Cohort: An Updated Review.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2019
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Tellervo KorhonenDepartment of Public Health, University of Helsinki, Helsinki, Finland; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland. Electronic address: tellervo.korhonen@helsinki.fi.
Elina SihvolaDepartment of Public Health, University of Helsinki, Helsinki, Finland; Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland.
Antti LatvalaDepartment of Public Health, University of Helsinki, Helsinki, Finland.
Danielle M DickDepartment of Psychology, Virginia Commonwealth University, Richmond, United States.
Lea PulkkinenDepartment of Psychology, University of Jyvaskyla, Jyvaskyla, Finland.
John NurnbergerDepartments of Psychiatry, Medical and Molecular Genetics, Indiana University, Indianapolis, United States.
Richard J RoseDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, United States.
Jaakko KaprioDepartment of Public Health, University of Helsinki, Helsinki, Finland; Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland.
University of Helsinki · FIHelsinki University Hospital · FIIndiana University Bloomington · USIndiana University – Purdue University Indianapolis · USInstitute for Molecular Medicine Finland · FIUniversity of Jyväskylä · FIVirginia Commonwealth University · US

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JESSICA E SALVATORE · 1989 to 2026
$162.7M
The development of alcohol misuse and related problems from adolescence to early midlifeR01AA015416 · NIAAA · WASHINGTON UNIVERSITY · PI DICK, DANIELLE M, SALVATORE, JESSICA E · 2005 to 2024
$7.6M
ADOLESCENT ALCOHOL ABUSE: A TWIN-STUDY PERSPECTIVER37AA012502 · NIAAA · TRUSTEES OF INDIANA UNIVERSITY · PI ROSE, RICHARD JOSEPH · 2000 to 2009
$2.9M
Twin, molecular, and developmental approaches to understanding alcohol misuseK02AA018755 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M · 2010 to 2019
$1.3M
Adolescent Alcohol Abuse: A Twin-Study PerspectiveR01AA012502 · NIAAA · TRUSTEES OF INDIANA UNIVERSITY · PI ROSE, RICHARD JOSEPH · 2013 to 2017
$1.2M
BEHAVIORAL PRECURSORS OF ALCOHOLISM--TWIN FAMILY STUDIESR01AA009203 · NIAAA · INDIANA UNIVERSITY BLOOMINGTON · PI ROSE, RICHARD JOSEPH · 1994 to 1998
–
USE &ABUSE OF ALCOHOL--A BEHAVIOR-GENETICS PERSPECTIVEK05AA000145 · NIAAA · INDIANA UNIVERSITY BLOOMINGTON · PI ROSE, RICHARD JOSEPH · 1992 to 1996
–
NIAAA NIH HHS K02 AA018755NIAAA NIH HHS K05 AA000145NIAAA NIH HHS R01 AA009203NIAAA NIH HHS R01 AA012502NIAAA NIH HHS R01 AA015416NIAAA NIH HHS R37 AA012502NIAAA NIH HHS U10 AA008401
6 · The paper itself

Abstract

backgroundDevelopmental relationships between tobacco use and suicide-related behaviors (SRB) remain unclear. Our objective was to investigate the longitudinal associations of tobacco use in adolescence and SRB in adulthood.

methodsUsing a prospective design, we examined whether tobacco use in adolescence is associated with SRB (intentional self-injury, suicide ideation) in young adulthood in a population-based sample of 1330 twins (626 males, 704 females). The baseline and follow-up data were collected by professionally administered semi-structured poly-diagnostic interviews at ages 14 and 22, respectively.

resultsAfter adjusting for multiple potential confounders, those who reported early-onset of regular tobacco use had a significantly increased risk for intentional self-injury, such as cutting or burning, at age 22 (adjusted odds ratio [AOR] 4.57, 95% CI 1.93-10.8) in comparison to those who had not at all initiated tobacco use. Also, daily cigarette smoking at baseline was associated with future intentional self-injury (AOR 4.45, 95% CI 2.04-9.70). Early-onset tobacco use was associated with suicidal ideation in females (AOR 3.69, 95% CI 1.56-8.72) but not in males. Considering any SRB, baseline daily smokers (AOR 2.13, 95% CI 1.12-4.07) and females with early onset of regular tobacco use (AOR 3.97, 95% CI 1.73-9.13) had an increased likelihood. Within-family analyses among twin pairs discordant for exposure and outcome controlling for familial confounds showed similar, albeit statistically non-significant, associations.

conclusionEarly-onset tobacco use in adolescence is longitudinally associated with SRB (intentional self-injury and/or suicide ideation) in young adulthood, particularly among females. Further investigation may reveal whether this association has implications for prevention of SRB in adolescence and young adulthood.

Indexed as

Suicidal IdeationAdolescentAge of OnsetCigarette SmokingFemaleFinlandHumansLongitudinal StudiesMaleOdds RatioProspective StudiesSelf-Injurious BehaviorSex FactorsSuicide, AttemptedTobacco UseYoung AdultSelf-injurySmokingSuicidal ideationTobaccoTwins

Identifiers

PMID29245024
PMCPMC5905715
OpenAlexW2772920361

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.