Evidence map›Paper›PMID 29244989›Full record

SynthesisJournal of global oncology2017

Global Use of Traditional and Complementary Medicine in Childhood Cancer: A Systematic Review.

Caroline Diorio, Catherine G Lam, Elena J Ladas, Festus Njuguna, Glenn M Afungchwi, Katherine Taromina, Stacey Marjerrison

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of global oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Guideline
  2. Interventions for the prevention of acute phase chemotherapy-induced nausea and vomiting in adult and pediatric patients: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  3. Development of an evidence-based decision aid on complementary and alternative medicine (CAM) and pain for parents of children with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caroline DiorioCaroline Diorio and Stacey Marjerrison, McMaster Children's Hospital, Hamilton, Ontario, Canada; Catherine G. Lam, St. Jude Children's Research Hospital, Memphis, TN; Elena J. Ladas and Katherine Taromina, Columbia University Medical Center, New York City, NY; Festus Njuguna, Moi University, Eldoret, Kenya; and Glenn M. Afungchwi, Banso Baptist Hospital, Kumbo, Cameroon.
Catherine G LamCaroline Diorio and Stacey Marjerrison, McMaster Children's Hospital, Hamilton, Ontario, Canada; Catherine G. Lam, St. Jude Children's Research Hospital, Memphis, TN; Elena J. Ladas and Katherine Taromina, Columbia University Medical Center, New York City, NY; Festus Njuguna, Moi University, Eldoret, Kenya; and Glenn M. Afungchwi, Banso Baptist Hospital, Kumbo, Cameroon.
Elena J LadasCaroline Diorio and Stacey Marjerrison, McMaster Children's Hospital, Hamilton, Ontario, Canada; Catherine G. Lam, St. Jude Children's Research Hospital, Memphis, TN; Elena J. Ladas and Katherine Taromina, Columbia University Medical Center, New York City, NY; Festus Njuguna, Moi University, Eldoret, Kenya; and Glenn M. Afungchwi, Banso Baptist Hospital, Kumbo, Cameroon.
Festus NjugunaCaroline Diorio and Stacey Marjerrison, McMaster Children's Hospital, Hamilton, Ontario, Canada; Catherine G. Lam, St. Jude Children's Research Hospital, Memphis, TN; Elena J. Ladas and Katherine Taromina, Columbia University Medical Center, New York City, NY; Festus Njuguna, Moi University, Eldoret, Kenya; and Glenn M. Afungchwi, Banso Baptist Hospital, Kumbo, Cameroon.
Glenn M AfungchwiCaroline Diorio and Stacey Marjerrison, McMaster Children's Hospital, Hamilton, Ontario, Canada; Catherine G. Lam, St. Jude Children's Research Hospital, Memphis, TN; Elena J. Ladas and Katherine Taromina, Columbia University Medical Center, New York City, NY; Festus Njuguna, Moi University, Eldoret, Kenya; and Glenn M. Afungchwi, Banso Baptist Hospital, Kumbo, Cameroon.
Katherine TarominaCaroline Diorio and Stacey Marjerrison, McMaster Children's Hospital, Hamilton, Ontario, Canada; Catherine G. Lam, St. Jude Children's Research Hospital, Memphis, TN; Elena J. Ladas and Katherine Taromina, Columbia University Medical Center, New York City, NY; Festus Njuguna, Moi University, Eldoret, Kenya; and Glenn M. Afungchwi, Banso Baptist Hospital, Kumbo, Cameroon.
Stacey MarjerrisonCaroline Diorio and Stacey Marjerrison, McMaster Children's Hospital, Hamilton, Ontario, Canada; Catherine G. Lam, St. Jude Children's Research Hospital, Memphis, TN; Elena J. Ladas and Katherine Taromina, Columbia University Medical Center, New York City, NY; Festus Njuguna, Moi University, Eldoret, Kenya; and Glenn M. Afungchwi, Banso Baptist Hospital, Kumbo, Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose Traditional and complementary medicine (T&CM) strategies are commonly used in pediatric oncology. Patterns may vary based on country income. We systematically reviewed published studies describing T&CM use among pediatric oncology patients in low-income countries (LIC/LMIC), middle-income countries (UMIC), and high-income countries (HIC). Objectives included describing estimated prevalence of use, reasons for use, perceived effectiveness, modalities used, rates of disclosure, and reporting of delayed or abandoned treatment. Methods MEDLINE, EMBASE, Global Health, CINAHL, PsycINFO, Allied and Complementary Medicine Database, Cochrane Database of Systematic Reviews, and ProceedingsFirst were searched. Inclusion criteria were primary studies involving children younger than the age of 18 years, undergoing active treatment of cancer, and any T&CM use. Exclusion criteria included no pediatric oncology-specific outcomes and studies involving only children off active treatment. Data were extracted by two reviewers using a systematic data extraction form determined a priori. Results Sixty-five studies published between 1977 and 2015 were included, representing 61 unique data sets and 7,219 children from 34 countries. The prevalence of T&CM use ranged from 6% to 100%. Median rates of use were significantly different in LIC/LMIC (66.7% ± 19%), UMIC (60% ± 26%), and HIC (47.2% ± 20%; P = .02). Rates of disclosure differed significantly by country income, with higher median rates in HIC. Seven studies reported on treatment abandonment or delays. Conclusion The use of T&CM in pediatric oncology is common worldwide, with higher median prevalence of use reported in LIC/LMIC. Further research is warranted to examine the impact on treatment abandonment and delay.

Indexed as

Global HealthAdolescentChildComplementary TherapiesFemaleHumansMaleMedicine, TraditionalNeoplasms

Identifiers

PMID29244989
PMCPMC5735959

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.