ArticlePloS one2017
Resistant and susceptible responses in alfalfa (Medicago sativa) to bacterial stem blight caused by Pseudomonas syringae pv. syringae.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 49 citations in OpenAlex.
- Unraveling alfalfa molecular adaptation to salinity andPlant signaling & behavior · 2025Article
- Histological and transcriptome analysis uncover a robust early PTI and ETI-associated immune response inFrontiers in plant science · 2025Article
- Defense and senescence interplay in legume nodules.Plant communications · 2024Review
- Genetic Mapping of Tolerance to Bacterial Stem Blight Caused byPlants (Basel, Switzerland) · 2023Article
- Alfalfa vein mottling virus, a novel potyvirid infecting Medicago sativa L.Virology journal · 2023Article
- Rhizobial nitrogen fixation efficiency shapes endosphere bacterial communities and Medicago truncatula host growth.Microbiome · 2023Article
- Identifications of QTLs and Candidate Genes Associated withInternational journal of molecular sciences · 2023Article
- The determination of the biological function of bacterial pink pigment andFrontiers in microbiology · 2023Article
- Multi-locus genome-wide association study of chickpea reference set identifies genetic determinants ofFrontiers in plant science · 2023Article
- OMICS in Fodder Crops: Applications, Challenges, and Prospects.Current issues in molecular biology · 2022Review
- Research Progress and Prospect of Alfalfa Resistance to Pathogens and Pests.Plants (Basel, Switzerland) · 2022Review
- Pan-transcriptome identifying master genes and regulation network in response to drought and salt stresses in Alfalfa (Medicago sativa L.).Scientific reports · 2021Article
- alfaNET: A Database of Alfalfa-Bacterial Stem Blight Protein-Protein Interactions Revealing the Molecular Features of the Disease-causing Bacteria.International journal of molecular sciences · 2021Article
- Transcriptome Profiling of Cucumber (International journal of molecular sciences · 2021Article
- Computational Systems Biology of Alfalfa - Bacterial Blight Host-Pathogen Interactions: Uncovering the Complex Molecular Networks for Developing Durable Disease Resistant Crop.Frontiers in plant science · 2021Article
- Plant defensin antibacterial mode of action against Pseudomonas species.BMC microbiology · 2020Article
- High-Throughput Sequencing for Deciphering the Virome of Alfalfa (Frontiers in microbiology · 2020Review
- Identification of emerging viral genomes in transcriptomic datasets of alfalfa (Medicago sativa L.).Virology journal · 2019Article
- Genomics of Plant Disease Resistance in Legumes.Frontiers in plant science · 2019Review
- Polyamines and Legumes: Joint Stories of Stress, Nitrogen Fixation and Environment.Frontiers in plant science · 2019Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial stem blight caused by Pseudomonas syringae pv. syringae is a common disease of alfalfa (Medicago sativa L). Little is known about host-pathogen interactions and host defense mechanisms. Here, individual resistant and susceptible plants were selected from cultivars Maverick and ZG9830 and used for transcript profiling at 24 and 72 hours after inoculation (hai) with the isolate PssALF3. Bioinformatic analysis revealed a number of differentially expressed genes (DEGs) in resistant and susceptible genotypes. Although resistant plants from each cultivar produced a hypersensitive response, transcriptome analyses indicated that they respond differently at the molecular level. The number of DEGs was higher in resistant plants of ZG9830 at 24 hai than in Maverick, suggesting that ZG9830 plants had a more rapid effector triggered immune response. Unique up-regulated genes in resistant ZG9830 plants included genes encoding putative nematode resistance HSPRO2-like proteins, orthologs for the rice Xa21 and soybean Rpg1-b resistance genes, and TIR-containing R genes lacking both NBS and LRR domains. The suite of R genes up-regulated in resistant Maverick plants had an over-representation of R genes in the CC-NBS-LRR family including two genes for atypical CCR domains and a putative ortholog of the Arabidopsis RPM1 gene. Resistance in both cultivars appears to be mediated primarily by WRKY family transcription factors and expression of genes involved in protein phosphorylation, regulation of transcription, defense response including synthesis of isoflavonoids, and oxidation-reduction processes. These results will further the identification of mechanisms involved in resistance to facilitate selection of parent populations and development of commercial varieties.
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