ArticlePediatric research2018
Prenatal and early postnatal measures of brain development and childhood sleep patterns.
Article in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Does the fortified milk with high iron dose improve the neurodevelopment of healthy infants? Randomized controlled trial.BMC pediatrics · 2019Trial
- Sleep and infant development in the first year.Pediatric research · 2026Article
- Modality-level obstacles and initiatives to improve representation in fetal, infant, and toddler neuroimaging research samples.Developmental cognitive neuroscience · 2025Article
- From Molecules to Mind: The Critical Role of Chitosan, Collagen, Alginate, and Other Biopolymers in Neuroprotection and Neurodegeneration.Molecules (Basel, Switzerland) · 2025Review
- The Impact of Sleep on Sensory Processing in Typically Developing Children: Insights from Cross-Sectional and Longitudinal Data.Children (Basel, Switzerland) · 2025Article
- Sleep problems at ages 8-9 and ADHD symptoms at ages 10-11: evidence in three cohorts from INMA study.European journal of pediatrics · 2023Article
- Sleep and 24-hour rhythm characteristics in preschool children born very preterm and full term.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Article
- The Architecture of Early Childhood Sleep Over the First Two Years.Maternal and child health journal · 2023Review
- Prenatal exposure to trans fatty acids and head growth in fetal life and childhood: triangulating confounder-adjustment and instrumental variable approaches.European journal of epidemiology · 2022Article
- Sleep and Executive Functioning in Pediatric Traumatic Brain Injury Survivors after Critical Care.Children (Basel, Switzerland) · 2022Article
- Effects of intergenerational exposure interventions on adolescent outcomes: An application of inverse probability weighting to longitudinal pre-birth cohort data.Paediatric and perinatal epidemiology · 2020Article
- Gestational age at birth and sleep duration in early childhood in three population-based cohorts.Sleep medicine: X · 2019Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundBrain development underlies maturation of sleep patterns throughout childhood. Intrauterine head growth-marker of early neurodevelopment-has not been associated with childhood sleep characteristics. We explored associations between ultrasonographic measures of prenatal and early postnatal neurodevelopment and childhood sleep.MethodsA total of 6,808 children from a population-based birth cohort (Generation R) were included. Head circumference (HC) and lateral ventricles size were assessed with mid- and late-pregnancy fetal ultrasounds, and with cranial ultrasound 3-20 weeks postnatally. Mothers reported children's sleep duration at 2 and 3 years, and sleep problems at 1.5, 3, and 6 years.ResultsLarger ventricular size, but not HC, was related to longer sleep duration at 3 years (β=0.06 h, 95% confidence interval (CI): 0.02; 0.10 in late-pregnancy and β=0.11 h, 95% CI: 0.02; 0.20 in early infancy, mid-pregnancy parameters were unrelated to sleep duration). Larger HC in mid-pregnancy was associated with a reduced risk for being a "problematic sleeper" up to the age of 6 years (odds ratio (OR): 0.94, 95% CI: 0.89; 0.99). Consistently, children with larger HC in early infancy were less likely to be "problematic sleepers" at 3 and 6 years.ConclusionsThis study shows that variations in fetal and neonatal brain size may underlie behavioral expression of sleep in childhood. Albeit small effect estimates, these associations provide evidence for neurodevelopmental origins of sleep.
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