Evidence map›Paper›PMID 29244743›Full record

Trial reportNutrients2017

Hematological and Hemodynamic Responses to Acute and Short-Term Creatine Nitrate Supplementation.

Ryan L Dalton, Ryan J Sowinski, Tyler J Grubic, Patrick B Collins, Adriana M Coletta, Aimee G Reyes, Brittany Sanchez, Majid Koozehchian, Yanghoon P Jung, Christopher Rasmussen and 4 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ryan L DaltonExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. ryanldalton@exchange.tamu.edu.
Ryan J SowinskiExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. ryansowinski6@gmail.com.
Tyler J GrubicExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. tylergrubic@tamu.edu.
Patrick B CollinsExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. blaise_collins@tamu.edu.
Adriana M ColettaExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. AMColetta@mdanderson.org.
Aimee G ReyesExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. agreyes1@exchange.tamu.edu.
Brittany SanchezExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. bksanchez@csub.edu.
Majid KoozehchianExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. mkoozehchian@jsu.edu.
Yanghoon P JungExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. yp.jung@cj.net.ORCID 0000-0002-9623-2150
Christopher RasmussenExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. crasmussen@tamu.edu.
Mike GreenwoodExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. mgreenwood26@tamu.edu.
Peter S MuranoInstitute for Obesity and Program Evaluation, Texas A & M University, College Station, TX 77843, USA. psmurano@tamu.edu.
Conrad P EarnestExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. conradearnest@exchange.tamu.edu.ORCID 0000-0002-6546-1268
Richard B KreiderExercise and Sport Nutrition Lab, Human Clinical Research Facility, Texas A & M University, College Station, TX 77843-4253, USA. rbkreider@tamu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a double-blind, crossover, randomized and placebo-controlled trial; 28 men and women ingested a placebo (PLA), 3 g of creatine nitrate (CNL), and 6 g of creatine nitrate (CNH) for 6 days. Participants repeated the experiment with the alternate supplements after a 7-day washout. Hemodynamic responses to a postural challenge, fasting blood samples, and bench press, leg press, and cycling time trial performance and recovery were assessed. Data were analyzed by univariate, multivariate, and repeated measures general linear models (GLM). No significant differences were found among treatments for hemodynamic responses, clinical blood markers or self-reported side effects. After 5 days of supplementation, one repetition maximum (1RM) bench press improved significantly for CNH (mean change, 95% CI; 6.1 [3.5, 8.7] kg) but not PLA (0.7 [-1.6, 3.0] kg or CNL (2.0 [-0.9, 4.9] kg, CNH,

Indexed as

Athletic PerformanceDietary SupplementsAdolescentAdultAnimalsAnthropometryBicyclingBody CompositionCreatineCross-Over StudiesDose-Response Relationship, DrugDouble-Blind MethodFemaleHemodynamicsHumansMaleCreatineNitratesPerformance-Enhancing Substancescreatinedietary supplementergogenic aidnitratesafety

Identifiers

PMID29244743
PMCPMC5748809

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.