Evidence map›Paper›PMID 29244532›Full record

ArticleThe American journal of sports medicine2018

Risk Factors and Predictors of Significant Chondral Surface Change From Primary to Revision Anterior Cruciate Ligament Reconstruction: A MOON and MARS Cohort Study.

MARS Group, Robert A Magnussen, James R Borchers, Angela D Pedroza, Laura J Huston, Amanda K Haas, Kurt P Spindler, Rick W Wright, Christopher C Kaeding, Christina R Allen and 87 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of sports medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Antero-lateral ligament reconstruction improves knee stability alongside anterior cruciate ligament reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Quadriceps tendon autograft is becoming increasingly popular in revision ACL reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Article
  15. Revision ACL Reconstruction: Principles and Practice.Indian journal of orthopaedics · 2021
    Review
  16. Article
  17. Article
  18. Predictors of clinical outcome following revision anterior cruciate ligament reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020
    Review
  19. Post-traumatic osteoarthritis diagnosed within 5 years following ACL reconstruction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

97 authors at 1 institution in 1 country.

MARS GroupInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Robert A MagnussenInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
James R BorchersInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Angela D PedrozaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Laura J HustonInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Amanda K HaasInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Kurt P SpindlerInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Rick W WrightInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Christopher C KaedingInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Christina R AllenInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Allen F AndersonInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Daniel E CooperInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Thomas M DeBerardinoInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Warren R DunnInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Brett A LantzInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Barton MannInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Michael J StuartInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
John P AlbrightInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Annunziato AmendolaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Jack T AndrishInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Christopher C AnnunziataInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Robert A ArcieroInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Bernard R BachInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Champ L BakerInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Arthur R BartolozziInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Keith M BaumgartenInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Jeffery R BechlerInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Jeffrey H BergInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Geoffrey A BernasInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Stephen F BrockmeierInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Robert H BrophyInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Charles A Bush-JosephInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
J Brad ButlerInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
John D CampbellInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
James L CareyInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
James E CarpenterInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Brian J ColeInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Jonathan M CooperInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Charles L CoxInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
R Alexander CreightonInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Diane L DahmInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Tal S DavidInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
David C FlaniganInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Robert W FrederickInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Theodore J GanleyInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Elizabeth A GarofoliInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Charles J GattInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Steven R GechaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
James Robert GiffinInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Sharon L HameInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Jo A HannafinInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Christopher D HarnerInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Norman Lindsay HarrisInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Keith S HechtmanInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Elliott B HershmanInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Rudolf G HoellrichInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Timothy M HoseaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
David C JohnsonInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Timothy S JohnsonInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Morgan H JonesInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Ganesh V KamathInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Thomas E KlootwykInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Bruce A LevyInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
C Benjamin MaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
G Peter MaiersInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Robert G MarxInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Matthew J MatavaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Gregory M MathienInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
David R McAllisterInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Eric C McCartyInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Robert G McCormackInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Bruce S MillerInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Carl W NissenInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Daniel F O'NeillInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Brett D OwensInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Richard D ParkerInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Mark L PurnellInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Arun J RamappaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Michael A RauhInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Arthur C RettigInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Jon K SekiyaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Kevin G SheaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Orrin H ShermanInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
James R SlauterbeckInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Matthew V SmithInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Jeffrey T SpangInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Steven J SvobodaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Timothy N TaftInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Joachim J TenutaInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Edwin M TingstadInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Armando F VidalInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Darius G ViskontasInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Richard A WhiteInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
James S WilliamsInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Michelle L WolcottInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Brian R WolfInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
James J YorkInvestigation performed at The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
The Ohio State University Wexner Medical Center · US

Funding

Revision ACL Reconstructions: A Comparative Effectiveness Treatment StudyR01AR060846 · NIAMS · WASHINGTON UNIVERSITY · PI WRIGHT, RICK W · 2011 to 2025
$6.7M
NIAMS NIH HHS R01 AR060846
6 · The paper itself

Abstract

backgroundArticular cartilage health is an important issue following anterior cruciate ligament (ACL) injury and primary ACL reconstruction. Factors present at the time of primary ACL reconstruction may influence the subsequent progression of articular cartilage damage. HYPOTHESIS: Larger meniscus resection at primary ACL reconstruction, increased patient age, and increased body mass index (BMI) are associated with increased odds of worsened articular cartilage damage at the time of revision ACL reconstruction. STUDY

designCase-control study; Level of evidence, 3.

methodsSubjects who had primary and revision data in the databases of the Multicenter Orthopaedics Outcomes Network (MOON) and Multicenter ACL Revision Study (MARS) were included. Reviewed data included chondral surface status at the time of primary and revision surgery, meniscus status at the time of primary reconstruction, primary reconstruction graft type, time from primary to revision ACL surgery, as well as demographics and Marx activity score at the time of revision. Significant progression of articular cartilage damage was defined in each compartment according to progression on the modified Outerbridge scale (increase ≥1 grade) or >25% enlargement in any area of damage. Logistic regression identified predictors of significant chondral surface change in each compartment from primary to revision surgery.

resultsA total of 134 patients were included, with a median age of 19.5 years at revision surgery. Progression of articular cartilage damage was noted in 34 patients (25.4%) in the lateral compartment, 32 (23.9%) in the medial compartment, and 31 (23.1%) in the patellofemoral compartment. For the lateral compartment, patients who had >33% of the lateral meniscus excised at primary reconstruction had 16.9-times greater odds of progression of articular cartilage injury than those with an intact lateral meniscus ( P < .001). For the medial compartment, patients who had <33% of the medial meniscus excised at the time of the primary reconstruction had 4.8-times greater odds of progression of articular cartilage injury than those with an intact medial meniscus ( P = .02). Odds of significant chondral surface change increased by 5% in the lateral compartment and 6% in the medial compartment for each increased year of age ( P ≤ .02). For the patellofemoral compartment, the use of allograft in primary reconstruction was associated with a 15-fold increased odds of progression of articular cartilage damage relative to a patellar tendon autograft ( P < .001). Each 1-unit increase in BMI at the time of revision surgery was associated with a 10% increase in the odds of progression of articular cartilage damage ( P = .046) in the patellofemoral compartment.

conclusionExcision of the medial and lateral meniscus at primary ACL reconstruction increases the odds of articular cartilage damage in the corresponding compartment at the time of revision ACL reconstruction. Increased age is a risk factor for deterioration of articular cartilage in both tibiofemoral compartments, while increased BMI and the use of allograft for primary ACL reconstruction are associated with an increased risk of progression in the patellofemoral compartment.

Indexed as

Anterior Cruciate Ligament ReconstructionAdolescentAdultAnterior Cruciate Ligament InjuriesBody Mass IndexCartilage, ArticularCase-Control StudiesFemaleHumansLogistic ModelsMaleMenisci, TibialPatellar LigamentProspective StudiesReoperationRisk FactorsACL reconstructionallograftarticular cartilageBMImeniscuspatellofemoral compartmentpatient-reported outcomes

Identifiers

PMID29244532
PMCPMC7004295
OpenAlexW2773001241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.