Evidence map›Paper›PMID 29244214›Full record

ArticleJournal of medical virology2018

Mixed viral infections of the respiratory tract; an epidemiological study during consecutive winter seasons.

Emmanouil Antalis, Zacharoula Oikonomopoulou, Christine Kottaridi, Athanasios Kossyvakis, Aris Spathis, Maria Magkana, Aikaterini Katsouli, Vassileios Tsagris, Vassiliki Papaevangelou, Andreas Mentis and 1 more

Abstract read
In one paragraph

Article in Journal of medical virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  3. Observational
  4. Review
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  6. Molecular detection of respiratory viruses: an observational study on respiratory co-infections in children and adults.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Observational
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
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  16. Mortality attributable to seasonal influenza in Greece, 2013 to 2017: variation by type/subtype and age, and a possible harvesting effect.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Emmanouil Antalis4th Department of Internal Medicine, University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Zacharoula Oikonomopoulou4th Department of Internal Medicine, University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Christine KottaridiDepartment of Cytopathology, University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Athanasios KossyvakisHellenic Pasteur Institute, Athens, Greece.
Aris SpathisDepartment of Cytopathology, University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Maria MagkanaDepartment of Cytopathology, University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Aikaterini Katsouli4th Department of Internal Medicine, University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Vassileios Tsagris3rd Department of Pediatrics, University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Vassiliki Papaevangelou3rd Department of Pediatrics, University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Andreas MentisHellenic Pasteur Institute, Athens, Greece.
Sotirios Tsiodras4th Department of Internal Medicine, University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.ORCID 0000-0002-0463-4321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study aimed to describe the molecular epidemiology of mixed respiratory viral infections during consecutive winter seasons in a tertiary care hospital. Patients with symptoms of respiratory tract infection were evaluated during the 2009-2011 and 2013-15 winter seasons. A clinical microarray technique was used for viral detection. Clinical and epidemiological data were correlated with mixed viral detection and the need for hospitalization. In 332 out of 604 (54.4%) evaluated patients (17.6% children) a respiratory virus was identified. Mixed viral infections were diagnosed in 68/332 (20.5%) patients with virus detection (66.2% mixed Influenza-RSV infections). Mixed viral infections were more commonly detected in children (OR 3.7; 95%CI 1.9-5.6, P < 0.01) and patients with comorbidities. In logistic regression analyses, mixed viral infections were associated with younger age (mean age 30.4 years vs. 41.8 years, P ≤ 0.001) and increased rates of fever (OR: 2.7; 95%CI 1.04-7.2, P < 0.05) but no adverse outcomes or increased rates of hospitalization. High rates of mixed viral infections were noted during all winter seasons (especially Influenza and RSV) and were more common in younger patients. The clinical significance of mixed respiratory viral infection needs further elucidation.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCoinfectionFemaleGreeceHospitalizationHumansInfantInfant, NewbornMaleMicroarray AnalysisMiddle Agedepidemiologyinfluenzarespiratory syncytial virus (RSV)

Identifiers

PMID29244214
PMCPMC7167177

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.