ArticleAmerican journal of epidemiology2018
Association of Maternal Psychosocial Stress With Increased Risk of Asthma Development in Offspring.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Perinatal maternal depression and the risk of childhood asthma in offspring: A meta-analysis.PloS one · 2024Pooled it
- Are prenatal anxiety or depression symptoms associated with asthma or atopic diseases throughout the offspring's childhood? An updated systematic review and meta-analysis.BMC pregnancy and childbirth · 2021Pooled it
- Maternal eating disorders and respiratory outcomes in childhood: findings from the EU Child Cohort Network.Thorax · 2026Article
- Childhood Environmental Exposures and Adult Disease.Pediatric pulmonology · 2026Review
- Maternal mental health disorders associate with their child's asthma: A register-based study.Brain, behavior, & immunity - health · 2025Article
- Antenatal depressive and anxiety symptoms in early pregnancy and offspring allergic diseases during toddlerhood.World journal of pediatrics : WJP · 2025Article
- Occupational psychosocial stressors and ergonomic strain during pregnancy and sex-specific risk of childhood asthma.International archives of occupational and environmental health · 2025Article
- Investigating the role of relationship satisfaction and paternal psychological distress during pregnancy on offspring health in early life.BJPsych open · 2023Article
- Using the Moving To Opportunity Experiment to Investigate the Long-Term Impact of Neighborhoods on Healthcare Use by Specific Clinical Conditions and Type of Service.Housing policy debate · 2023Article
- Parental mental health, socioeconomic position and the risk of asthma in children-a nationwide Danish register study.European journal of public health · 2022Article
- S3 guideline Allergy Prevention.Allergologie select · 2022Article
- Maternal stress and depression are associated with respiratory phenotypes in urban children.The Journal of allergy and clinical immunology · 2021Article
- Associations Between Maternal Lifetime Stress and Placental Mitochondrial DNA Mutations in an Urban Multiethnic Cohort.Biological psychiatry · 2021Article
- Maternal Depressive Symptoms, Lung Function, and Severe Asthma Exacerbations in Puerto Rican Children.The journal of allergy and clinical immunology. In practice · 2021Article
- Maternal life and work stressors during pregnancy and asthma in offspring.International journal of epidemiology · 2021Article
- Prenatal Maternal Stress Exacerbates Experimental Colitis of Offspring in Adulthood.Frontiers in immunology · 2021Article
- Fetal-Derived Immune Cells at the Roots of Lifelong Pathophysiology.Frontiers in cell and developmental biology · 2021Review
- Article
- Advances and novel developments in environmental influences on the development of atopic diseases.Allergy · 2020Review
- Genetic liability to major depression and risk of childhood asthma.Brain, behavior, and immunity · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
Abstract
Prenatal maternal psychosocial stress might influence the development of childhood asthma. Evaluating paternal psychosocial stress and conducting a sibling comparison could provide further insight into the role of unmeasured confounding. We examined the associations of parental psychosocial stress during and after pregnancy with asthma at age 7 years in the Norwegian Mother and Child Cohort Study (n = 63,626; children born in 2000-2007). Measures of psychosocial stress included lifetime major depressive symptoms, current anxiety/depression symptoms, use of antidepressants, anxiolytics, and/or hypnotics, life satisfaction, relationship satisfaction, work stress, and social support. Childhood asthma was associated with maternal lifetime major depressive symptoms (adjusted relative risk (aRR) = 1.19, 95% confidence interval (CI): 1.09, 1.30), in addition to symptoms of anxiety/depression during pregnancy (aRR = 1.17, 95% CI: 1.06, 1.29) and 6 months after delivery (aRR = 1.17, 95% CI: 1.07, 1.28). Maternal negative life events during pregnancy (aRR = 1.10, 95% CI: 1.06, 1.13) and 6 months after delivery (aRR = 1.14, 95% CI: 1.11, 1.18) were also associated with asthma. These associations were not replicated when evaluated within sibling groups. There were no associations with paternal psychosocial stress. In conclusion, maternal anxiety/depression and negative life events were associated with offspring asthma, but this might be explained by unmeasured maternal background characteristics that remain stable across deliveries.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.