ArticleNanotoxicology2018
Reactive oxygen species damage drives cardiac and mitochondrial dysfunction following acute nano-titanium dioxide inhalation exposure.
Abstract read
In one paragraph
Article in Nanotoxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Common Gene Expression Patterns in Environmental Model Organisms Exposed to Engineered Nanomaterials: A Meta-Analysis.Environmental science & technology · 2020Pooled it
- Biological Safety Analysis of Nanoparticles: Exploring Toxicity, Mechanisms, and Safety Factors for Pharmaceuticals.International journal of nanomedicine · 2026Review
- Article
- Single pulmonary nanopolystyrene exposure in late-stage pregnancy dysregulates maternal and fetal cardiovascular function.Toxicological sciences : an official journal of the Society of Toxicology · 2024Article
- NNanotoxicology · 2023Article
- In Vitro Safety Assessment of In-House Synthesized Titanium Dioxide Nanoparticles: Impact of Washing and Temperature Conditions.International journal of molecular sciences · 2023Article
- Insights into Ag-NPs-mediated pathophysiology and ultrastructural aberrations in ovarian tissues of darkling beetles.Scientific reports · 2022Article
- Indirect mediators of systemic health outcomes following nanoparticle inhalation exposure.Pharmacology & therapeutics · 2022Review
- Maternal Nanomaterial Inhalation Exposure: Critical Gestational Period in the Uterine Microcirculation is Angiotensin II Dependent.Cardiovascular toxicology · 2022Article
- Transcriptomics of single dose and repeated carbon black and ozone inhalation co-exposure highlight progressive pulmonary mitochondrial dysfunction.Particle and fibre toxicology · 2021Article
- Chronic exposure to tramadol induces cardiac inflammation and endothelial dysfunction in mice.Scientific reports · 2021Article
- Enhanced antioxidant capacity prevents epitranscriptomic and cardiac alterations in adult offspring gestationally-exposed to ENM.Nanotoxicology · 2021Article
- Composable Microfluidic Plates (cPlate): A Simple and Scalable Fluid Manipulation System for Multiplexed Enzyme-Linked Immunosorbent Assay (ELISA).Analytical chemistry · 2021Article
- Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy.Particle and fibre toxicology · 2020Article
- Titanium dioxide nanoparticles exaggerate respiratory syncytial virus-induced airway epithelial barrier dysfunction.American journal of physiology. Lung cellular and molecular physiology · 2020Article
- Cardiovascular adaptations to particle inhalation exposure: molecular mechanisms of the toxicology.American journal of physiology. Heart and circulatory physiology · 2020Review
- Effects of oral administration of titanium dioxide particles on sperm parameters andVeterinary research forum : an international quarterly journal · 2020Article
- Effect of Gestational Age on Maternofetal Vascular Function Following Single Maternal Engineered Nanoparticle Exposure.Cardiovascular toxicology · 2019Article
- ROS promote epigenetic remodeling and cardiac dysfunction in offspring following maternal engineered nanomaterial (ENM) exposure.Particle and fibre toxicology · 2019Article
- miRNA-378a as a key regulator of cardiovascular health following engineered nanomaterial inhalation exposure.Nanotoxicology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Cody E Nicholsa Division of Exercise Physiology , West Virginia University School of Medicine , Morgantown , WV , USA.
Danielle L Shepherda Division of Exercise Physiology , West Virginia University School of Medicine , Morgantown , WV , USA.
Quincy A Hathawaya Division of Exercise Physiology , West Virginia University School of Medicine , Morgantown , WV , USA.
Andrya J Durra Division of Exercise Physiology , West Virginia University School of Medicine , Morgantown , WV , USA.
Dharendra Thapaa Division of Exercise Physiology , West Virginia University School of Medicine , Morgantown , WV , USA.
Alaeddin Abukabdad Department of Physiology and Pharmacology , West Virginia University School of Medicine , Morgantown , WV , USA.
Jinghai Yid Department of Physiology and Pharmacology , West Virginia University School of Medicine , Morgantown , WV , USA.
Timothy R Nurkiewiczc Mitochondria, Metabolism and Bioenergetics Working Group , West Virginia University School of Medicine , Morgantown , WV , USA.
John M Hollandera Division of Exercise Physiology , West Virginia University School of Medicine , Morgantown , WV , USA.
West Virginia University · USBioEnergetics (United States) · US
Funding
THE ROLE OF HEF1 PROTEIN IN INVASION OF METASTATIC BREAST CANCERP20RR016440 · NCRR · WEST VIRGINIA UNIVERSITY · PI CUFF, CHRISTOPHER F · 2001 to 2010
$22.8MGenetic Analyses For Epidemiologic Studies Of Respiratory DiseaseZIAES025045 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$7.3MGenetic And Environmental Factors In Childhood Respiratory HealthZIAES049019 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LONDON, STEPHANIE · 2009 to 2025
$6.8MRemote Microvascular Dysfunction After Particulate Matter ExposureR01ES015022 · NIEHS · WEST VIRGINIA UNIVERSITY · PI NURKIEWICZ, TIMOTHY R · 2007 to 2021
$4.9MWest Virginia Flow Cytometry Core FacilityP30GM103488 · NIGMS · WEST VIRGINIA UNIVERSITY · PI CUFF, CHRISTOPHER F · 2012 to 2016
$4.8MmiRNA Regulation of the Mitochondrial GenomeR01HL128485 · NHLBI · WEST VIRGINIA UNIVERSITY · PI HOLLANDER, JOHN M · 2017 to 2019
$1.3MVisual Sonics Vevo 2100 Imaging SystemS10RR026378 · NCRR · WEST VIRGINIA UNIVERSITY · PI MARTIN, KAREN H · 2010 to 2010
$454kmiRNA Regulation of the Mitochondrial GenomeR56HL128485 · NHLBI · WEST VIRGINIA UNIVERSITY · PI HOLLANDER, JOHN M · 2015 to 2015
$410kAmerican Heart Association-American Stroke Association 17PRE33660333Intramural NIH HHS Z99 ES999999Intramural NIH HHS ZIA ES025045Intramural NIH HHS ZIA ES049019NCRR NIH HHS P20 RR016440NCRR NIH HHS S10 RR026378NHLBI NIH HHS R01 HL128485NHLBI NIH HHS R56 HL128485NIEHS NIH HHS R01 ES015022NIGMS NIH HHS P30 GM103488
Abstract
Nanotechnology offers innovation in products from cosmetics to drug delivery, leading to increased engineered nanomaterial (ENM) exposure. Unfortunately, health impacts of ENM are not fully realized. Titanium dioxide (TiO
Indexed as
Administration, InhalationAnimalsAntioxidantsGlutathione PeroxidaseHeartMaleMiceMice, TransgenicMitochondriaNanostructuresOxidative StressPhospholipid Hydroperoxide Glutathione PeroxidaseReactive Oxygen SpeciesTitaniumAntioxidantsGlutathione PeroxidasePhospholipid Hydroperoxide Glutathione PeroxidaseReactive Oxygen SpeciesTitaniumtitanium dioxideantioxidantcardiac functionMitochondriareactive oxygen speciestitanium dioxide
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What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.