ArticleeLife2017
Human subthalamic nucleus activity during non-motor decision making.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 60 citations in OpenAlex.
- Linking reduced prefrontal microcircuit inhibition in schizophrenia to EEG biomarkers in silico.PLoS computational biology · 2026Article
- Subthalamic nucleus in patients with Parkinson's disease encodes changes and magnitude of applied force.NPJ Parkinson's disease · 2026Article
- Beta bursts mediate amygdala gating of hippocampal emotional encoding.bioRxiv : the preprint server for biology · 2025Article
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- Unraveling the roles of spatial working memory sustained and selective neurons in prefrontal cortex.Communications biology · 2025Article
- Modulating food craving-related neural oscillations using tACS: study protocol for a randomized sham-controlled trial.Frontiers in human neuroscience · 2025Article
- Oscillatory activity in bilateral prefrontal cortices is altered by distractor strength during working memory processing.NeuroImage · 2024Article
- Prefrontal-subthalamic theta signaling mediates delayed responses during conflict processing.Progress in neurobiology · 2024Article
- Subthalamic Activity for Motor Execution and Cancelation in Monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Architecture of the subthalamic nucleus.Communications biology · 2024Review
- Uncovering the neurophysiology of mood, motivation and behavioral symptoms in Parkinson's disease through intracranial recordings.NPJ Parkinson's disease · 2023Review
- Repeated Transcranial Photobiomodulation with Light-Emitting Diodes Improves Psychomotor Vigilance and EEG Networks of the Human Brain.Bioengineering (Basel, Switzerland) · 2023Article
- The Effects of Subthalamic Nucleus Deep Brain Stimulation and Retention Delay on Memory-Guided Reaching Performance in People with Parkinson's Disease.Journal of Parkinson's disease · 2023Article
- Conflict Detection in a Sequential Decision Task Is Associated with Increased Cortico-Subthalamic Coherence and Prolonged Subthalamic Oscillatory Response in the β Band.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Biophysical and Architectural Mechanisms of Subthalamic Theta under Response Conflict.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
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- Movement-related beta ERD and ERS abnormalities in neuropsychiatric disorders.Frontiers in neuroscience · 2022Review
- Modelling and prediction of the dynamic responses of large-scale brain networks during direct electrical stimulation.Nature biomedical engineering · 2021Article
- Modulation of neural oscillations during working memory update, maintenance, and readout: An hdEEG study.Human brain mapping · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Recent studies have implicated the subthalamic nucleus (STN) in decisions that involve inhibiting movements. Many of the decisions that we make in our daily lives, however, do not involve any motor actions. We studied non-motor decision making by recording intraoperative STN and prefrontal cortex (PFC) electrophysiology as participants perform a novel task that required them to decide whether to encode items into working memory. During all encoding trials, beta band (15-30 Hz) activity decreased in the STN and PFC, and this decrease was progressively enhanced as more items were stored into working memory. Crucially, the STN and lateral PFC beta decrease was significantly attenuated during the trials in which participants were instructed not to encode the presented stimulus. These changes were associated with increase lateral PFC-STN coherence and altered STN neuronal spiking. Our results shed light on why states of altered basal ganglia activity disrupt both motor function and cognition.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.