Evidence map›Paper›PMID 29243255›Full record

ArticleThe Laryngoscope2018

Viscoelastic properties of human aryepiglottic fold and ventricular fold tissues at phonatory frequencies.

Miwako Kimura, Roger W Chan

Open access · greenAbstract read
In one paragraph

Article in The Laryngoscope, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Miwako KimuraDepartment of Otolaryngology, University of Tokyo Hospital, Tokyo, Japan.
Roger W ChanDepartment of Speech Language Pathology and Audiology, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.ORCID 0000-0002-7135-9702
National Taipei University of Nursing and Health Science · TWUniversity of Tokyo Hospital · JP

Funding

Biomechanical Characterization of Vocal Fold TissuesR01DC006101 · NIDCD · UT SOUTHWESTERN MEDICAL CENTER · PI CHAN, ROGER W · 2003 to 2012
$3.7M
NIDCD NIH HHS R01 DC006101
6 · The paper itself

Abstract

objectiveThe purpose of this study was to quantify the viscoelastic shear properties of the human ventricular fold (or false vocal fold) mucosa and aryepiglottic fold mucosa at frequencies of phonation.

methodsLinear viscoelastic shear properties of the mucosa of false vocal fold and aryepiglottic fold specimens from seven cadaveric subjects were determined as functions of frequency (5-250 Hz) and compared to those of the true vocal fold cover. Measurements of elastic shear modulus (G') and dynamic viscosity (η') were made with a controlled-strain simple-shear rheometer. Linear least-squares regression was conducted to curve-fit log G' and log η' versus log frequency, and statistical analysis was performed with one-way analysis of variance.

resultsAll specimens showed similar frequency dependence of the viscoelastic functions G' and η', with G' gradually increasing with frequency and η' monotonically decreasing with frequency. The magnitudes of G' and η' of the false fold mucosa were generally higher than those of the aryepiglottic fold mucosa and true vocal fold cover, but there were no significant differences in G' and η' among the false fold, aryepiglottic fold, and true vocal fold.

conclusionThe false vocal fold and aryepiglottic fold mucosa showed similar frequency dependence and a similar range of tissue viscoelastic behavior as the true vocal fold. These preliminary findings suggested that such tissues could become candidates for the replacement of the true vocal fold lamina propria in patients with significant tissue loss and deficiencies, for those requiring laryngeal reconstruction following partial laryngectomy or airway reconstruction. LEVEL OF EVIDENCE: NA. Laryngoscope, E296-E301, 2018.

Indexed as

AdultAgedAged, 80 and overAnalysis of VarianceCadaverElasticityFemaleHumansLaryngeal MucosaLeast-Squares AnalysisMaleMiddle AgedPhonationPlethysmography, ImpedanceViscosityVocal Cordsaryepiglottic foldelasticityRheometryventricular fold phonationviscosity

Identifiers

PMID29243255
PMCPMC6003822
OpenAlexW2774707133

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.