Evidence map›Paper›PMID 29243108›Full record

ArticleStem cell reviews and reports2018

Identification of a Novel High Yielding Source of Multipotent Adult Human Neural Crest-Derived Stem Cells.

Matthias Schürmann, Viktoria Brotzmann, Marlena Bütow, Johannes Greiner, Anna Höving, Christian Kaltschmidt, Barbara Kaltschmidt, Holger Sudhoff

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Article in Stem cell reviews and reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Neural crest-like stem cells for tissue regeneration.Stem cells translational medicine · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matthias SchürmannDepartment of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld, Teutoburger Straße 50, 33604, Bielefeld, Germany.
Viktoria BrotzmannDepartment of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld, Teutoburger Straße 50, 33604, Bielefeld, Germany.
Marlena BütowDepartment of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld, Teutoburger Straße 50, 33604, Bielefeld, Germany.
Johannes GreinerDepartment of Cell Biology, University of Bielefeld, 33615, Bielefeld, Germany.
Anna HövingDepartment of Cell Biology, University of Bielefeld, 33615, Bielefeld, Germany.
Christian KaltschmidtDepartment of Cell Biology, University of Bielefeld, 33615, Bielefeld, Germany.
Barbara KaltschmidtDepartment of Cell Biology, University of Bielefeld, 33615, Bielefeld, Germany.
Holger SudhoffDepartment of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld, Teutoburger Straße 50, 33604, Bielefeld, Germany. holger.sudhoff@rub.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to their extraordinarily broad differentiation potential and persistence during adulthood, adult neural crest-derived stem cells (NCSCs) are highly promising candidates for clinical applications, particularly when facing the challenging treatment of neurodegenerative diseases or complex craniofacial injuries. Successful application of human NCSCs in regenerative medicine and pharmaceutical research mainly relies on the availability of sufficient amounts of tissue for cell isolation procedures. Facing this challenge, we here describe for the first time a novel population of NCSCs within the middle turbinate of the human nasal cavity. From a surgical point of view, high amounts of tissue are routinely and easily removed during nasal biopsies. Investigating the presence of putative stem cells in obtained middle turbinate tissue by immunohistochemistry, we observed Nestin

Indexed as

AdipogenesisAdult Stem CellsCell DifferentiationCells, CulturedFemaleFlow CytometryHumansImmunohistochemistryMaleMesenchymal Stem CellsNasal CavityNeural CrestNeural Stem CellsNeuronsOsteoblastsReal-Time Polymerase Chain ReactionAdult stem cellsHumanMiddle turbinateNasal cavityNCSCsNeural crest

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.