Evidence map›Paper›PMID 29243104›Full record

ArticleDigestive diseases and sciences2018

Skepticism Regarding Vaccine and Gluten-Free Food Safety Among Patients with Celiac Disease and Non-celiac Gluten Sensitivity.

Loren G Rabinowitz, Haley M Zylberberg, Alan Levinovitz, Melissa S Stockwell, Peter H R Green, Benjamin Lebwohl

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Article in Digestive diseases and sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Loren G RabinowitzDepartment of Medicine, Celiac Disease Center, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Haley M ZylberbergDepartment of Medicine, Celiac Disease Center, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Alan LevinovitzDepartment of Philosophy and Religion, James Madison University, Harrisonburg, VA, USA.
Melissa S StockwellDepartment of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Peter H R GreenDepartment of Medicine, Celiac Disease Center, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Benjamin LebwohlDepartment of Medicine, Celiac Disease Center, Columbia University College of Physicians and Surgeons, New York, NY, USA. BL114@columbia.edu.
Columbia University · USJames Madison University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere has been a marked increase in the adoption of the gluten-free (GF) diet.

aimsTo query individuals with celiac disease (CD) and non-celiac gluten sensitivity (NCGS) on their beliefs toward the health effects of gluten, and safety of vaccines and GF food products.

methodsWe distributed a Web-based survey to individuals with CD and NCGS on a CD center e-mail list. We used univariate and multivariate analysis to compare responses of respondents with CD and NCGS.

resultsThe overall response rate was 27% (NCGS n = 217, CD n = 1291). Subjects with NCGS were more likely than those with CD to disagree with the statement that "vaccines are safe for people with celiac disease" (NCGS 41.3% vs. CD 26.4% (p < 0.0001), and were more likely to decline vaccination when offered (30.9 vs. 24.2%, p = 0.007). After adjusting for age and gender, NCGS subjects were more likely than CD subjects to avoid genetically modified (GMO) foods (aOR 2.30; 95% CI 1.71-3.10), eat only organic products (aOR 2.87; 95% CI 2.04-4.03), believe that the FDA is an unreliable source of information (aOR 1.82, 95% CI 1.26-2.64), and believe a GF diet improves energy and concentration (aOR 2.52; 95% CI 1.86-3.43).

conclusionsSubjects with NCGS were more likely than those with CD to have doubts about vaccine safety and believe in the value of non-GMO and organic foods. Our findings suggest that the lack of reliable information on gluten and its content in food and medications may reinforce beliefs that result in a detriment to public health.

Indexed as

Food SafetyHealth Knowledge, Attitudes, PracticeAdolescentAdultAgedAged, 80 and overCeliac DiseaseDiet, Gluten-FreeFemaleFood, Genetically ModifiedFood HypersensitivityFood, OrganicGlutensHumansMaleMiddle AgedGlutensVaccinesCeliac diseaseGlutenNon-celiac gluten sensitivityVaccines

Identifiers

PMID29243104
OpenAlexW2771553257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.