ArticleMolecular and cellular biochemistry2018
Translational regulation in the anoxic turtle, Trachemys scripta elegans.
Article in Molecular and cellular biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Patterns of Local Adaptation in the Northern Leopard Frog (Evolutionary applications · 2026Article
- A comprehensive embryonic staging series of the turtle Trachemys scripta.Developmental dynamics : an official publication of the American Association of Anatomists · 2026Article
- Phosphoproteomic changes in response to anoxia are tissue-specific in the anoxia-tolerant crucian carp (Frontiers in physiology · 2024Article
- Role of unfolded protein response and ER-associated degradation under freezing, anoxia, and dehydration stresses in the freeze-tolerant wood frogs.Cell stress & chaperones · 2023Article
- Regulation of Apoptosis and Autophagy During Anoxia in the Freshwater Crayfish, Faxonius virilis.Marine biotechnology (New York, N.Y.) · 2022Review
- mTOR Signaling in Metabolic Stress Adaptation.Biomolecules · 2021Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The red-eared slider turtle (Trachemys scripta elegans), has developed remarkable adaptive mechanisms for coping with decreased oxygen availability during winter when lakes and ponds become covered with ice. Strategies for enduring anoxia tolerance include an increase in fermentable fuel reserves to support anaerobic glycolysis, the buffering of end products to minimize acidosis, altered expression in crucial survival genes, and strong metabolic rate suppression to minimize ATP-expensive metabolic processes such as protein synthesis. The mammalian target of rapamycin (mTOR) is at the center of the insulin-signaling pathway that regulates protein translation. The present study analyzed the responses of the mTOR signaling pathway to 5 (5H) or 20 h (20H) of anoxic submergence in liver and skeletal muscle of T. scripta elegans with a particular focus on regulatory changes in the phosphorylation states of targets. The data showed that phosphorylation of multiple mTOR targets was suppressed in skeletal muscle, but activated in the liver. Phosphorylated mTOR
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Registered trials
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