Evidence map›Paper›PMID 29242832›Full record

ArticlemSphere

Persistence of Supplemented

Steven A Frese, Andra A Hutton, Lindsey N Contreras, Claire A Shaw, Michelle C Palumbo, Giorgio Casaburi, Gege Xu, Jasmine C C Davis, Carlito B Lebrilla, Bethany M Henrick and 6 more

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 155 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 6 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02457338 naactive not recruitingnot on this map

Infant Supplementation With Probiotic Bifidobacterium Longum Subsp. Infantis Study

TypeinterventionalSponsorUniversity of California, DavisRan2014 to 2027Enrolled120ConditionsHealthyArmsBifidobacterium
NCT04662619 nacompletednot on this map

A Proof-of-Concept, Randomized, Double-Blind, Placebo-Controlled, Two-Arm, Parallel-Group, Nutritional Intervention Study to Examine the Clinical and Immunological Effects of a Probiotic Food Supplement Containing B. Infantis (EVC001) in Healthy Breastfed Infants at Risk of Developing Atopic Dermatitis

TypeinterventionalSponsorJohnson & Johnson Consumer Inc. (J&JCI)Ran2020 to 2024Enrolled273ConditionsHealthyArmsB. infantis, Lactose Placebo
3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 6 syntheses or guidelines pooled it, 220 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Improving immune-related health outcomes post-cesarean birth with a gut microbiome-based program: A randomized controlled trial.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Trial
  10. Safety and Tolerance ofNutrients · 2025
    Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Pediatrics · 2019
    Trial

95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Steven A FreseEvolve Biosystems, Inc., Davis, California, USA.ORCID 0000-0003-2053-5830
Andra A HuttonEvolve Biosystems, Inc., Davis, California, USA.ORCID 0000-0002-5522-6643
Lindsey N ContrerasEvolve Biosystems, Inc., Davis, California, USA.ORCID 0000-0001-6074-5467
Claire A ShawEvolve Biosystems, Inc., Davis, California, USA.ORCID 0000-0002-2495-0612
Michelle C PalumboEvolve Biosystems, Inc., Davis, California, USA.
Giorgio CasaburiEvolve Biosystems, Inc., Davis, California, USA.ORCID 0000-0002-5980-8704
Gege XuDepartment of Chemistry, University of California, Davis, California, USA.
Jasmine C C DavisDepartment of Chemistry, University of California, Davis, California, USA.
Carlito B LebrillaDepartment of Chemistry, University of California, Davis, California, USA.
Bethany M HenrickFoods for Health Institute, University of California, Davis, California, USA.ORCID 0000-0003-1883-6749
Samara L FreemanEvolve Biosystems, Inc., Davis, California, USA.
Daniela BarileFoods for Health Institute, University of California, Davis, California, USA.ORCID 0000-0002-3889-1596
J Bruce GermanFoods for Health Institute, University of California, Davis, California, USA.
David A MillsFoods for Health Institute, University of California, Davis, California, USA.ORCID 0000-0003-1913-9865
Jennifer T SmilowitzFoods for Health Institute, University of California, Davis, California, USA.
Mark A UnderwoodFoods for Health Institute, University of California, Davis, California, USA.
University of California, Davis · USUC Davis Children's Hospital · US

Funding

Activation of probiotic bifidobacteria by milk glyansR01AT008759 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GERMAN, BRUCE, LEBRILLA, CARLITO B · 2014 to 2018
$4.2M
Mechanism of Activation of Probiotic Bifidobacteria by Prebiotic Milk GlycansR01AT007079 · NCCIH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GERMAN, BRUCE, LEBRILLA, CARLITO B · 2012 to 2016
$2.2M
NCCIH NIH HHS R01 AT007079NCCIH NIH HHS R01 AT008759
6 · The paper itself

Abstract

Attempts to alter intestinal dysbiosis via administration of probiotics have consistently shown that colonization with the administered microbes is transient. This study sought to determine whether provision of an initial course of

Indexed as

bifidobacteriabreast milkhuman milk oligosaccharidesinfant microbiome

Identifiers

PMID29242832
PMCPMC5717325
OpenAlexW2772189975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.