ArticleClinical Medicine Insights. Oncology2017
Clinical Characteristics of Patients With Renal Cell Carcinoma and Metastasis to the Thyroid Gland.
Article in Clinical Medicine Insights. Oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Clear Cell Renal Cell Carcinoma Metastasis to the Thyroid: A Narrative Review of the Literature.Cancers · 2025Review
- Sites of Metastasis and Survival in Metastatic Renal Cell Carcinoma: Results From the Korean Renal Cancer Study Group Database.Journal of Korean medical science · 2024Article
- Improving Anticancer Drug Selection and Prioritization via Neural Learning to Rank.Journal of chemical information and modeling · 2024Article
- Clinicopathological and Molecular Features of Secondary Cancer (Metastasis) to the Thyroid and Advances in Management.International journal of molecular sciences · 2022Review
- Late-Onset Metastatic Renal Cell Carcinoma to the Thyroid Gland: An Unusual Airway Emergency.The American journal of case reports · 2022Article
- Renal cell carcinoma with unusual metachronous metastasis up to 22 years after nephrectomy: two case reports.Journal of medical case reports · 2021Article
- Pancreatic tropism of metastatic renal cell carcinoma.JCI insight · 2020Article
- A Rare Case of Metastasis of Renal Clear Cell Carcinoma to the Thyroid Gland, Presenting as a Goiter Nodule, Three Years After Nephrectomy.Iranian journal of pathology · 2020Article
- Merkel cell carcinoma: an aggressive cutaneous carcinoma with rare metastasis to the thyroid gland.BMJ case reports · 2019Article
- Didactic surgical experience of thyroid metastasis from renal cell carcinoma: A case report.World journal of clinical cases · 2018Article
- Tumor Biology is King: Secondary Tumors of the Thyroid From 2 Medical Centers in China.Cancer control : journal of the Moffitt Cancer CenterArticle
- Internist's tumour into thyroid: A case report.Journal of the West African College of SurgeonsArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
introductionRenal cell carcinoma (RCC) is the most common malignancy to metastasize to the thyroid gland. The aims of this study are as follows: (1) to analyze the clinical characteristics of patients with thyroid involvement of RCC and (2) in patients with RCC thyroid metastasis, to determine whether RCC metastasis to glandular organs only portends a better prognosis compared with other patterns of RCC metastasis.
methodsPatients from Wake Forest Baptist Medical Center (WFBMC) diagnosed with thyroid metastasis from RCC were identified and medical records retrospectively examined. A systematic review of the literature for cases of RCC involving the thyroid gland was also performed. The clinical characteristics of the institutional cohort and the cases from the literature review were compared. Descriptive statistical analysis was performed, and overall survival (OS) was summarized using Kaplan-Meier methods.
resultsThe median OS for the WFBMC cohort was 56.4 months. In the literature review cohort, OS of patients with RCC thyroid metastasis was 213.6 months, and there was no statistically significant survival difference based on the site of metastasis. Median survival after thyroid metastasis from RCC for the WFBMC and literature cohort was 21.6 and 45.6 months, respectively.
conclusionsMetastatic RCC should be included in the differential of a new thyroid mass. Treatment directed at the thyroid metastasis results in prolonged survival in some cases. Further analysis into the genomic differences and mechanisms of thyroid metastasis is warranted.
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