ArticleScientific reports2017
A Coxiella mutualist symbiont is essential to the development of Rhipicephalus microplus.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
79 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Prevalence ofFrontiers in veterinary science · 2021Pooled it
- Epidemiological investigation of a clinical case of Q fever in the Brazilian Amazon.Parasite epidemiology and control · 2026Article
- Genomic Evolution of Francisella: Metabolic Innovation, Endosymbiotic Transitions to Ticks, and Biogeographic History.Genome biology and evolution · 2026Article
- Feeding-state is associated with shifts in the Haemaphysalis bispinosa microbiome and its potential as a sentinel for circulating livestock pathogens.Veterinary research communications · 2026Article
- RmTIL, a cysteine-rich protein as a putative microbiota modulator from Rhipicephalus microplus tick.Parasitology research · 2026Article
- Adaptive restructuring of the microbiota promotes overwintering survival of the tick Dermacentor silvarum.Parasites & vectors · 2026Article
- High throughput sequencing in the diagnosis and surveillance of tick-borne diseases: A narrative review.One health (Amsterdam, Netherlands) · 2026Review
- Genetic diversity of Haemaphysalis longicornis populations in China and their symbiotic association with Coxiella R1 strain.Experimental & applied acarology · 2026Article
- Transcriptome of Coxiella-like endosymbionts in Haemaphysalis longicornis during blood feeding.The Journal of veterinary medical science · 2026Article
- Rhipicephalus sanguineus s.l. ticks (Acari: Ixodidae) harbor non-divergent bacterial microbiomes in Arizona.Journal of medical entomology · 2026Article
- First evidence of naturally vertically transmitted Coxiella-like endosymbionts in Haemaphysalis bispinosa from dairy cattle in Indonesia.Scientific reports · 2026Article
- Advances in the use of entomopathogenic fungi to control ixodid ticks.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2026Review
- Coxiella burnetii in ruminants from Somalia.Tropical animal health and production · 2025Article
- An insight into the draft genome of the Oriental rat flea, Xenopsylla cheopis, together with its Wolbachia endosymbiont.BMC genomics · 2025Article
- Tick genomics through a Nanopore: a low-cost approach for tick genomics.BMC genomics · 2025Article
- Evolutionary Convergence of Nutritional Symbionts in Ticks.Environmental microbiology reports · 2025Article
- Exploring the microbiomes of camel ticks to infer vector competence: insights from tissue-level symbiont-pathogen relationships.Scientific reports · 2025Article
- Culturable bacteria and fungi in Ixodes, Dermacentor, Amblyomma and Ornithodoros ticks.Parasite (Paris, France) · 2025Article
- Genetic and genomic variability ofISME communications · 2025Article
- Metatranscriptomics provide insights into the role of the symbiont Midichloria mitochondrii in Ixodes ticks.FEMS microbiology ecology · 2024Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cattle tick Rhipicephalus microplus is a hematophagous ectoparasite that causes important economic losses in livestock. Different species of ticks harbor a symbiont bacterium of the genus Coxiella. It was showed that a Coxiella endosymbiont from R. microplus (CERM) is a vertically transmitted mutualist symbiont, comprising 98% of the 16S rRNA sequences in both eggs and larvae. Sequencing of the bacterial genome revealed genes for biosynthetic pathways for several vitamins and key metabolic cofactors that may provide a nutritional complement to the tick host. The CERM was abundant in ovary and Malpighian tubule of fully engorged female. Tetracycline treatment of either the tick or the vertebrate host reduced levels of bacteria in progeny in 74% for eggs and 90% for larvae without major impact neither on the reproductive fitness of the adult female or on embryo development. However, CERM proved to be essential for the tick to reach the adult life stage, as under antibiotic treatment no tick was able to progress beyond the metanymph stage. Data presented here suggest that interference in the symbiotic CERM-R. microplus relationship may be useful to the development of alternative control methods, highlighting the interdependence between ticks and their endosymbionts.
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