Evidence map›Paper›PMID 29242532›Full record

ArticleBlood cancer journal2017

Jagged1-induced Notch activation contributes to the acquisition of bortezomib resistance in myeloma cells.

Yukari Muguruma, Takashi Yahata, Takayuki Warita, Katsuto Hozumi, Yoshihiko Nakamura, Rikio Suzuki, Mamoru Ito, Kiyoshi Ando

Abstract readLetter
In one paragraph

Article in Blood cancer journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Targeting NOTCH3 to eradicate dormant and therapy-resistant multiple myeloma cells.Journal of experimental & clinical cancer research : CR · 2026
    Article
  3. Review
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  13. Article
  14. Review
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  16. Review
  17. The multifunctional role of Notch signaling in multiple myeloma.Journal of cancer metastasis and treatment · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yukari MugurumaCenter for Regenerative Medicine, Tokai University School of Medicine, Isehara, Japan. yuknakay@ncc.go.jp.
Takashi YahataCenter for Regenerative Medicine, Tokai University School of Medicine, Isehara, Japan.
Takayuki WaritaCenter for Regenerative Medicine, Tokai University School of Medicine, Isehara, Japan.
Katsuto HozumiDepartment of Immunology, Tokai University School of Medicine, Isehara, Japan.
Yoshihiko NakamuraCenter for Regenerative Medicine, Tokai University School of Medicine, Isehara, Japan.
Rikio SuzukiDepartment of Hematology and Oncology, Tokai University School of Medicine, 143 Shimokasuya Isehara, Kanagawa, 259-1193, Isehara, Japan.
Mamoru ItoCentral Institute for Experimental Animals, Kawasaki, Japan.
Kiyoshi AndoCenter for Regenerative Medicine, Tokai University School of Medicine, Isehara, Japan. andok@keyaki.cc.u-tokai.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBortezomibDrug Resistance, NeoplasmEnzyme ActivationHumansJagged-1 ProteinMiceMice, Inbred NODMice, SCIDMultiple MyelomaReceptors, NotchSignal TransductionXenograft Model Antitumor AssaysBortezomibJAG1 protein, humanJagged-1 ProteinReceptors, Notch

Identifiers

PMID29242532
PMCPMC5802593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.