ArticleAnnals of transplantation2017
The Evolution of Corneal Transplantation.
Article in Annals of transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- 3D Differentiation of Bone-Marrow Derived Mesenchymal Stromal Cells into the Keratocyte Lineage for Corneal Bioprinting.Advanced healthcare materials · 2025Article
- Advances in corneal transplantation.Eye (London, England) · 2025Review
- A historical view of the development of corneal transplantation: from penetrating keratoplasty to selective transplantation of the finest corneal layers.Wiener medizinische Wochenschrift (1946) · 2025Review
- Long-term outcomes of corneal transplantation: a review of 8,378 patients.BMC ophthalmology · 2025Article
- Stapler for corneal transplantation: a hypothesis.Medical hypothesis, discovery & innovation ophthalmology journal · 2025Article
- Descemet's membrane endothelial keratoplasty for primary graft failure after penetrating keratoplasty.Arquivos brasileiros de oftalmologia · 2022Article
- Corneal fibrosis abrogation by a localized AAV-mediated inhibitor of differentiation 3 (Id3) gene therapy in rabbit eyes in vivo.Molecular therapy : the journal of the American Society of Gene Therapy · 2022Article
- Exposure of Ophthalmology Residents to Cornea and Keratorefractive Surgeries in the United States.Journal of academic ophthalmology (2017) · 2022Article
- Effects of femtosecond laser-assisted trephination on donor tissue in liquid interface as compared to applanated interface.Acta ophthalmologica · 2022Article
- Evolution of corneal transplantation techniques and their indications in a French corneal transplant unit in 2000-2020.PloS one · 2022Article
- Corneal transplantation activity in Catalonia, Spain, from 2011 to 2018: Evolution of indications and surgical techniques.PloS one · 2021Article
- Changing Indications for Penetrating Keratoplasty in Bahrain in a Tertiary Referral Centre.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Variable Responses to Corneal Grafts: Insights from Immunology and Systems Biology.Journal of clinical medicine · 2020Review
- Exploring the Key Genes and Pathways in the Formation of Corneal Scar Using Bioinformatics Analysis.BioMed research international · 2020Article
- Corneal transplantation in the modern era.The Indian journal of medical research · 2019Review
- Corneal transplantation: A walk to vision.Medical journal, Armed Forces IndiaReview
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND The aim of this study was to investigate the evolution of surgical methods in and leading indications for corneal transplantation from 2005 to 2016. MATERIAL AND METHODS Data from the corneal graft waiting list and from all keratoplasties carried out between 2005 and 2016 at the University Eye Hospital Tübingen were retrospectively evaluated. RESULTS A total of 1259 keratoplasties were performed between 2005 and 2016 at the University Eye Hospital Tübingen. The most common surgical indications for corneal transplantation were Fuchs endothelial corneal dystrophy (45.5%) and keratoconus (14.2%). The mean rate of corneal transplantations almost doubled from 71 keratoplasties per year in the first 6-year period to 139 keratoplasties per year in the second 6-year period (P=0.005). The number of penetrating keratoplasties remained similar. The number of Descemet membrane endothelial keratoplasties (DMEK) increased significantly from 2008 to 2016 (P<0.0001). One DMEK procedure was performed in 2008 (representing 1.4% of all transplantations), while 75 DMEK procedures were performed in 2016 (representing 60.5% of all transplantations) (P<0.0001). DMEK became the favored surgical method for endothelial disorders, exceeding penetrating keratoplasty in 2013. CONCLUSIONS Our study shows evolutionary changes in preferred corneal transplantation techniques and leading indications for keratoplasty from 2005 to 2016. Since its introduction a decade ago, DMEK is currently the golden standard in the management of corneal endothelial dysfunction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.