Evidence map›Paper›PMID 29242385›Full record

ArticleG3 (Bethesda, Md.)2018

Differential Regulation of

Lucas T Laudermilk, Joseph M Thomas, Samir N Kelada

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Baseline and innate immune response characterization of a Zfp30 knockout mouse strain.Mammalian genome : official journal of the International Mammalian Genome Society · 2020
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lucas T LaudermilkDepartment of Genetics, University of North Carolina at Chapel Hill, North Carolina 27599.
Joseph M ThomasDepartment of Genetics, University of North Carolina at Chapel Hill, North Carolina 27599.
Samir N KeladaDepartment of Genetics, University of North Carolina at Chapel Hill, North Carolina 27599 samir_kelada@med.unc.edu.ORCID 0000-0003-2676-9232
University of North Carolina at Chapel Hill · USLung Institute · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
Gene-Environment Interactions with Ozone in Experimental AsthmaR01ES024965 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KELADA, SAMIR · 2015 to 2019
$2.2M
Systems-level transcriptomic analyses to Identify mouse models of asthmaR01HL122711 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KELADA, SAMIR · 2015 to 2018
$2.0M
NHLBI NIH HHS R01 HL122711NIEHS NIH HHS P30 ES010126NIEHS NIH HHS R01 ES024965
6 · The paper itself

Abstract

Neutrophil chemotaxis to the airways is a key aspect of host response to microbes and a feature of multiple pulmonary diseases including asthma. Tight regulation of this recruitment is critical to prevent unwanted host tissue damage and inflammation. Using a mouse (

Indexed as

Gene Expression RegulationPolymorphism, Single NucleotideAnimalsCell LineDNA-Binding ProteinsHaplotypesMice, 129 StrainMice, Inbred C57BLMice, Inbred StrainsPromoter Regions, GeneticProtein BindingQuantitative Trait LociRespiratory MucosaTranscription FactorsDNA-Binding ProteinsTranscription FactorsZfp148 protein, mouseZfp30 protein, mousecausal variantCXCL1eQTLneutrophilZFP148Zfp30

Identifiers

PMID29242385
PMCPMC5919737
OpenAlexW2774282636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.