Evidence map›Paper›PMID 29242293›Full record

ArticleHaematologica2018

Variable impairment of platelet functions in patients with severe, genetically linked immune deficiencies.

Magdolna Nagy, Tom G Mastenbroek, Nadine J A Mattheij, Susanne de Witt, Kenneth J Clemetson, Janbernd Kirschner, Ansgar S Schulz, Thomas Vraetz, Carsten Speckmann, Attila Braun and 3 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Suppressed ORAI1-STIM1-dependent CaThe Journal of biological chemistry · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Ultra-high-throughput CaiScience · 2022
    Article
  11. The Missing Pieces to the Cold-Stored Platelet Puzzle.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. ORAI1 CaFrontiers in cell and developmental biology · 2021
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Magdolna NagyDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Tom G MastenbroekDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Nadine J A MattheijDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Susanne de WittDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Kenneth J ClemetsonDepartment of Haematology, Inselspital, University of Bern, Switzerland.
Janbernd KirschnerDepartment of Neuropediatrics and Muscle Disorders, Medical Center, University of Freiburg, Germany.
Ansgar S SchulzDepartment of Pediatrics and Adolescent Medicine, University Medical Centre Ulm, Germany.
Thomas VraetzDepartment of Pediatrics and Adolescent Medicine, Medical Center-University of Freiburg, Faculty of Medicine, Germany.
Carsten SpeckmannCenter for Chronic Immunodeficiency and Department of Pediatrics and Adolescent Medicine, Medical Centre, University of Freiburg, Germany.
Attila BraunInstitute of Experimental Biomedicine, University Hospital and Rudolf Virchow Centre, University of Würzburg, Germany.
Judith M E M CosemansDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.
Barbara ZiegerCenter for Chronic Immunodeficiency and Department of Pediatrics and Adolescent Medicine, Medical Centre, University of Freiburg, Germany.
Johan W M HeemskerkDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands jwm.heemskerk@maastrichtuniversity.nl.
Maastricht University · NLUniversity of Freiburg · DEUniversity Hospital of Bern · CHUniversity Hospital Ulm · DEUniversity Medical Center Freiburg · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with dysfunctions of the Ca

Indexed as

CalciumHumansImmunologic Deficiency SyndromesMembrane ProteinsMutationNeoplasm ProteinsORAI1 ProteinPlatelet ActivationPlatelet AdhesivenessPlatelet AggregationPlatelet Function TestsStromal Interaction Molecule 1ThrombosisCalciumFERMT3 protein, humanMembrane ProteinsNeoplasm ProteinsORAI1 ProteinSTIM1 protein, humanStromal Interaction Molecule 1

Identifiers

PMID29242293
PMCPMC5830379
OpenAlexW2771736938

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.