Evidence map›Paper›PMID 29241542›Full record

ArticleCell reports2017

MICU2 Restricts Spatial Crosstalk between InsP

Riley Payne, Henry Hoff, Anne Roskowski, J Kevin Foskett

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 93 citations in OpenAlex.

  1. Asymmetric distribution of mitochondrial CaExperimental & molecular medicine · 2026
    Article
  2. Mechanistic Modeling of MCUx Gatekeeping, CaAmerican journal of physiology. Cell physiology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. TMEM65 functions as the mitochondrial NaNature cell biology · 2025
    Article
  7. Review
  8. Article
  9. HRP2 regulating MICU1-mediated CaNeoplasia (New York, N.Y.) · 2025
    Article
  10. Calcium signaling in mitochondrial intermembrane space.Biochemical Society transactions · 2024
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. IGF-1 boosts mitochondrial function by a CaFrontiers in physiology · 2023
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Riley PayneDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Henry HoffDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Anne RoskowskiDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
J Kevin FoskettDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: foskett@mail.med.upenn.edu.
University of Pennsylvania · US

Funding

Multidisciplinary Training in Cardiovascular BiologyT32HL007954 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DAVIES, PETER FRANCIS · 2000 to 2019
$9.9M
Electrophysiology of nuclear membrane InsP3 receptorR37GM056328 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI FOSKETT, JAMES KEVIN · 2011 to 2020
$4.9M
ELECTROPHYSIOLOGY OF NUCLEAR MEMBRANE INSP3 RECEPTORR01GM056328 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI FOSKETT, JAMES KEVIN · 1999 to 2010
$4.2M
BIOLOGICAL ROLES OF NODAL RELATED GENES IN EMBRYOGENESISR01GM056238 · NIGMS · VANDERBILT UNIVERSITY · PI WRIGHT, CHRISTOPHER V · 1997 to 2010
$2.8M
NHLBI NIH HHS T32 HL007954NIGMS NIH HHS R01 GM056238NIGMS NIH HHS R01 GM056328NIGMS NIH HHS R37 GM056328
6 · The paper itself

Abstract

Ca

Indexed as

CalciumCalcium-Binding ProteinsCalcium ChannelsCalcium SignalingCations, DivalentCation Transport ProteinsGene Expression RegulationHEK293 CellsHumansInositol 1,4,5-Trisphosphate ReceptorsIon TransportMembrane Potential, MitochondrialMitochondriaMitochondrial Membrane Transport ProteinsProtein BindingProtein MultimerizationCalciumCalcium-Binding ProteinsCalcium ChannelsCations, DivalentCation Transport ProteinsInositol 1,4,5-Trisphosphate ReceptorsMICU1 protein, humanMICU2 protein, humanmitochondrial calcium uniporterMitochondrial Membrane Transport Proteinscalciuminositol trisphosphate receptormitochondriananodomainuniporter

Identifiers

PMID29241542
PMCPMC5734103
OpenAlexW2775114564

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.