Evidence map›Paper›PMID 29241403›Full record

ArticleNeuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition2019

Social support and verbal interaction are differentially associated with cognitive function in midlife and older age.

Megan L Zuelsdorff, Rebecca L Koscik, Ozioma C Okonkwo, Paul E Peppard, Bruce P Hermann, Mark A Sager, Sterling C Johnson, Corinne D Engelman

Abstract read
In one paragraph

Article in Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. The Association Between Social Isolation, Functional Social Support, and Memory: A Mediation Analysis of the Canadian Longitudinal Study on Aging.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
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  8. Neighborhood-level socioeconomic disadvantage is associated with multiple cognitive domains in a community sample of older adults.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Megan L Zuelsdorffa Alzheimer's Disease Research Center , University of Wisconsin School of Medicine and Public Health , Madison , WI , USA.
Rebecca L Koscikc University of Wisconsin - Madison , Madison , WI , USA.
Ozioma C Okonkwoa Alzheimer's Disease Research Center , University of Wisconsin School of Medicine and Public Health , Madison , WI , USA.
Paul E Peppardc University of Wisconsin - Madison , Madison , WI , USA.
Bruce P Hermanna Alzheimer's Disease Research Center , University of Wisconsin School of Medicine and Public Health , Madison , WI , USA.
Mark A Sagerc University of Wisconsin - Madison , Madison , WI , USA.
Sterling C Johnsona Alzheimer's Disease Research Center , University of Wisconsin School of Medicine and Public Health , Madison , WI , USA.ORCID 0000-0002-8501-545X
Corinne D Engelmana Alzheimer's Disease Research Center , University of Wisconsin School of Medicine and Public Health , Madison , WI , USA.

Funding

Wisconsin Registry for Alzheimer's Prevention: Sex Differences in DNA MethylationR01AG027161 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Nathaniel Ark Chin, Sterling C Johnson · 2007 to 2026
$35.6M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Wisconsin Registry for Alzheimer's PreventionRF1AG027161 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, STERLING C · 2018 to 2018
$18.8M
Wisconsin Alzheimer's Disease Research CenterP50AG033514 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CHAPPELL, RICHARD J · 2009 to 2018
$16.2M
Center for Demography and EcologyR24HD047873 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI RAYMO, JAMES M · 2004 to 2013
$7.2M
POPULATION, LIFE COURSE, AND AGINGT32AG000129 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Michal Engelman · 1986 to 2026
$6.0M
Health Disparities Research Scholars Training Program-RenewalT32HD049302 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Maureen S Durkin · 2007 to 2026
$5.6M
Scientific and Technical CoreP2CHD047873 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine J. Curtis · 2014 to 2026
$5.1M
NCATS NIH HHS UL1 TR000427NIA NIH HHS P50 AG033514NIA NIH HHS R01 AG027161NIA NIH HHS RF1 AG027161NIA NIH HHS T32 AG000129NICHD NIH HHS R24 HD047873NICHD NIH HHS T32 HD049302
6 · The paper itself

Abstract

Social engagement is associated with healthy aging and preserved cognition. Two dimensions of engagement, verbal interactions and perceived support, likely impact cognition via distinct mechanistic pathways. We explored the cognitive benefit of each construct among enrollees (N = 1,052, mean age = 60.2 years) in the Wisconsin Registry for Alzheimer's Prevention study, who provide neuropsychological and sociobehavioral data at two-year intervals. Outcomes included six cognitive factor scores representing key domains of executive function and memory. Key predictors included self-reported perceived social support and weekly verbal interaction. Results indicated that after adjusting for lifestyle covariates, social support was positively associated with Speed and Flexibility and that verbal interactions were associated with Verbal Learning and Memory. These findings suggest that support, which may buffer stress, and verbal interaction, an accessible, aging-friendly form of environmental enrichment, are uniquely beneficial. Both are integral in the design of clinical and community interventions and programs that promote successful aging.

Indexed as

Interpersonal RelationsRegistriesSocial SupportAgedAgingExecutive FunctionFemaleHumansMaleMemoryMiddle AgedVerbal Behaviorcognitionenvironmental enrichmentsocial activitySocial networks

Identifiers

PMID29241403
PMCPMC6003840

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.