Evidence map›Paper›PMID 29241081›Full record

ArticleAddictive behaviors2018

Does misuse lead to a disorder? The misuse of prescription tranquilizer and sedative medications and subsequent substance use disorders in a U.S. longitudinal sample.

C J Boyd, B West, S E McCabe

Abstract read
In one paragraph

Article in Addictive behaviors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. Prescription Drug Misuse: Taking a Lifespan Perspective.Substance abuse : research and treatment · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C J BoydCenter for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, MI, 48109, USA; Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI 48109, USA; Addiction Center, Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: caroboyd@umich.edu.
B WestSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI 48106, USA.
S E McCabeCenter for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, MI, 48109, USA; Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: plius@umich.edu.
University of Michigan–Ann Arbor · US

Funding

Trajectories of Prescription Nonmedical Drug MisuseR01DA031160 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEAN ESTEBAN MCCABE · 2011 to 2026
$3.7M
Longitudinal Changes in Recovery from Drug Use Disorders: A National StudyR01DA036541 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCABE, SEAN ESTEBAN · 2015 to 2017
$647k
NIDA NIH HHS R01 DA031160NIDA NIH HHS R01 DA036541
6 · The paper itself

Abstract

objectivesWe used two waves of National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) data and examined whether the misuse of prescription tranquilizers or sedatives at Wave 1 was associated with either continued misuse, tranquilizer/sedative use disorder, or other substance use disorder (SUD) at Wave 2.

methodsProspective data were analyzed from structured diagnostic interviews using the Alcohol Use disorders and Associated Disabilities Interview Schedule: DSM-IV Version (AUDADIS-DSM-IV). A nationally representative sample of 34,653 of U.S. adults, 18years or older at Wave 1 (2001-2002), were re-interviewed at Wave 2 (2004-2005). After applying the survey weights, the sample represented a population that was 52% female, 71% White, 12% Hispanic, 11% African American, 4% Asian and 2% Native American or other.

resultsAn estimated 79% of adults who engaged in tranquilizer or sedative misuse at Wave 1 had stopped using these drugs at Wave 2. Only a small percentage (4.3%) of misusers at Wave 1 had a tranquilizer or sedative use disorder at Wave 2. However, 45% (45.0%) of misusers at Wave 1 had at least one other SUD at Wave 2. Among those in remission from a sedative or tranquilizer use disorder at Wave 1, 4.8% had a tranquilizer or sedative use disorder while 34.7% had at least one other SUD at Wave 2.

conclusionsMost adults who engaged in the misuse of prescription tranquilizers or sedatives ceased using within 3years; however, their prior misuse was associated with higher prevalence of having a SUD three years later.

Indexed as

Hypnotics and SedativesTranquilizing AgentsAdolescentAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedPrescription Drug MisusePrevalenceSubstance-Related DisordersUnited StatesYoung AdultHypnotics and SedativesTranquilizing AgentsDrug use disordersPrescription drug misuseSedative medication misuseSubstance abuseTranquilizer medication misuse

Identifiers

PMID29241081
PMCPMC5884701
OpenAlexW2769038896

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.