Evidence map›Paper›PMID 29241006›Full record

ReviewBioconjugate chemistry2018

Toxoid Vaccination against Bacterial Infection Using Cell Membrane-Coated Nanoparticles.

Pavimol Angsantikul, Ronnie H Fang, Liangfang Zhang

Abstract readReview
In one paragraph

Review in Bioconjugate chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Antibiotic Alternatives and Next-Generation Therapeutics forAntibiotics (Basel, Switzerland) · 2025
    Review
  3. Bacterial exotoxins in medicine: potential value and perspectives.International journal of medical sciences · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Subunit vaccines forFrontiers in immunology · 2022
    Review
  13. Review
  14. Article
  15. Review
  16. Bacteria-Inspired Nanomedicine.ACS applied bio materials · 2021
    Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pavimol AngsantikulDepartment of NanoEngineering and Moores Cancer Center , University of California San Diego , La Jolla , California 92093 , United States.
Ronnie H FangDepartment of NanoEngineering and Moores Cancer Center , University of California San Diego , La Jolla , California 92093 , United States.
Liangfang ZhangDepartment of NanoEngineering and Moores Cancer Center , University of California San Diego , La Jolla , California 92093 , United States.ORCID 0000-0003-0637-0654
University of California San Diego · US

Funding

Nanotherapeutics for Ocular InfectionsR01EY025947 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI CALLEGAN, MICHELLE C, ZHANG, LIANGFANG · 2015 to 2017
$1.1M
NEI NIH HHS R01 EY025947
6 · The paper itself

Abstract

As nanoparticles exhibit unique properties attractive for vaccine development, they have been progressively implemented as antigen delivery platforms and immune potentiators. Recently, cell membrane-coated nanoparticles have provided a novel approach for intercepting and neutralizing bacterial toxins by leveraging their natural affinity to cellular membranes. Such toxin-nanoparticle assemblies, termed nanotoxoids, allow rapid loading of different types of toxins and have been investigated for their ability to effectively confer protection against bacterial infection. This topical review will cover the current progress in antibacterial vaccine nanoformulations and highlight the nanotoxoid platform as a novel class of nanoparticulate vaccine. We aim to provide insights into the potential of nanotoxoids as a platform that is facile to implement and can be broadly applied to help address the rising threat of super pathogens.

Indexed as

AnimalsBacteriaBacterial InfectionsBacterial ToxinsBacterial VaccinesCell MembraneHumansNanoparticlesNanotechnologyToxoidsVaccinationVaccines, SubunitBacterial ToxinsBacterial VaccinesToxoidsVaccines, Subunit

Identifiers

PMID29241006
PMCPMC5893865
OpenAlexW2774708386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.