ArticlePloS one2017
Is quality of life different between diabetic and non-diabetic people? The importance of cardiovascular risks.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Multilayer perceptron modeling of health literacy and medication adherence determinants in Arab patients with cardiometabolic disease: the role of quality of life, eating behaviors, and physical activity.BMC research notes · 2026Article
- Biomarker signatures distinguish diabetic retinopathy and diabetic nephropathy.Diabetology international · 2025Article
- Determinants of Health-Related Quality of Life in Outpatients with Myocardial Infarction.Journal of multidisciplinary healthcare · 2024Article
- Association of multimorbidity and changes in health-related quality of life following myocardial infarction: a UK multicentre longitudinal patient-reported outcomes study.BMC medicine · 2021Article
- Epidemiology and Economic Burden of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus in Spain: A Systematic Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021Review
- A case-control study of pattern and determinants of quality of life of patients with diabetes in a developing country.The Journal of the Egyptian Public Health Association · 2021Article
- Impact of non-cardiovascular comorbidities on the quality of life of patients with chronic heart failure: a scoping review.Health and quality of life outcomes · 2020Article
- Incidence and costs of cardiovascular events in Spanish patients with type 2 diabetes mellitus: a comparison with general population, 2015.BMJ open diabetes research & care · 2020Observational
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Authors and funding
6 authors.
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Abstract
backgroundTo analyse and compare the impact of cardiovascular risk factors and disease on health-related quality of life (HRQoL) in people with and without diabetes living in the community.
methodsWe used data of 1,905 people with diabetes and 19,031 people without diabetes from the last Spanish National Health Survey (years 2011-2012). The HRQoL instrument used was the EuroQol 5D-5L, based on time trade-off scores. Matching methods were used to assess any differences in the HRQoL in people with and without diabetes with the same characteristics (age, gender, education level, and healthy lifestyle), according to cardiovascular risk factors and diseases. Disparities were also analysed for every dimension of HRQoL: mobility, daily activities, personal care, pain/discomfort, and anxiety/depression.
resultsThere were no significant differences in time trade-off scores between people with and without diabetes when cardiovascular risk factors or established cardiovascular disease were not present. However, when cardiovascular risk factors were present, the HRQoL score was significantly lower in people with diabetes than in those without. This difference was indeed greater when cardiovascular diseases were present. More precisely, people with diabetes and any of the cardiovascular risk factors, who have not yet developed any cardiovascular disease, report lower HRQoL, 0.046 TTO score points over 1 (7.93 over 100 in the VAS score) compared to those without diabetes, and 0.14 TTO score points of difference (14.61 over 100 in the VAS score) if cardiovascular diseases were present. In fact, when the three risk factors were present in people with diabetes, HRQoL was significantly lower (0.10 TTO score points over 1 and 10.86 points over 100 in VAS score), obesity being the most influential risk factor.
conclusionsThe presence of established cardiovascular disease and/or cardiovascular risk factors, specially obesity, account for impaired quality of life in people with diabetes.
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