ArticleInternational journal of environmental research and public health2017
Prevalence of Albuminuria in Children Living in a Rural Agricultural and Fishing Subsistence Community in Lake Chapala, Mexico.
Article in International journal of environmental research and public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Screening for urinary abnormalities in healthy school children living in an African urban megacity.BMC nephrology · 2026Article
- Vanadium exposure and kidney markers in a pediatric population: a cross-sectional study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Article
- Children's exposure to herbicides in Jalisco, Mexico-a public health concern perspective.Frontiers in public health · 2025Article
- Frequency of urinary pesticides in children: a scoping review.Frontiers in public health · 2023Article
- Non-traditional risk factors of progression of chronic kidney disease in adult population: a scoping review.Frontiers in medicine · 2023Article
- Urinary cystatin C: pediatric reference intervals and comparative assessment as a biomarker of renal injury among children in the regions with high burden of CKDu in Sri Lanka.World journal of pediatrics : WJP · 2022Article
- Chronic kidney disease of unknown etiology in India: a comparative study with Mesoamerican and Sri Lankan nephropathy.Environmental science and pollution research international · 2022Review
- Social determinants and chronic kidney disease of undetermined origin in childhood: Its communication and understanding described by families in Lake Chapala, Mexico.Frontiers in nephrology · 2022Article
- Sustainable Development Goals relevant to kidney health: an update on progress.Nature reviews. Nephrology · 2021Review
- Is an Environmental Nephrotoxin the Primary Cause of CKDu (Mesoamerican Nephropathy)? CON.Kidney360 · 2020Article
- Urinary Pesticide Levels in Children and Adolescents Residing in Two Agricultural Communities in Mexico.International journal of environmental research and public health · 2019Article
- Seasonal Urinary Levels of Glyphosate in Children From Agricultural Communities.Dose-response : a publication of International Hormesis SocietyArticle
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Authors and funding
6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The occurrence of Chronic Kidney Disease (CKD) of unknown etiology in autochthonous child populations residing along the Lake Chapala lakeshore is endemic (Jalisco, México). The objective of this study was to determine the prevalence of albuminuria in the pediatric population and to measure the glomerular filtration rate in children with two positive albuminuria tests. Urinary albumin was measured in 394 children. Subjects with two or more positive albuminuria test donated blood samples for the determination of serum biomarkers. From a rural community with 565 children under the age of 17 years, 394 (69.7%) participated with first morning urine samples. A total of 180 children were positive (with two or more positive albuminuria tests). The prevalence of albuminuria among the children participating in the study was 45.7%. Of the 180 children with persistent albuminuria, 160 (88.9%) were tested for serum creatinine, urea, and cystatin C. The 68.1% of the children studied, were found in stages 3a and 3b of the Kidney Disease Improving Global Outcomes (KDIGO) classification (mean glomerular filtration rate (GFR) 51.9 and 38.4 mL/min/1.73 m² respectively). The lowest frequencies were for classifications 1 and 4. None of the subjects was classified as grade 5. The prevalence of albuminuria in children from this rural community is 3-5 times higher than reported in international literature. Regarding GFR, more than 50% of children studied are under 60 mL/min/1.73 m². It is a priority to find the causes of albuminuria and CKD in this Mexican region.
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