ArticleInternational journal of molecular sciences2017
Fibrinogen as a Pleiotropic Protein Causing Human Diseases: The Mutational Burden of Aα, Bβ, and γ Chains.
Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Clinical manifestations, diagnosis and treatment of hereditary fibrinogen Aα-chain renal amyloidosis: one case report and systematic review.International urology and nephrology · 2025Pooled it
- Arachidonic Acid Metabolic Rewiring Drives Differential Plant Protein Adaptation in Golden Pompano (International journal of molecular sciences · 2026Article
- Gynecologic and obstetric complications in women with congenital fibrinogen disorders: insights from the Prospective Rare Bleeding Disorders Database.Research and practice in thrombosis and haemostasis · 2025Article
- The thrombotic paradox in congenital fibrinogen deficiencies: from pathophysiology to practice.Research and practice in thrombosis and haemostasis · 2025Review
- Functional characterisation of missense ceruloplasmin variants and real-world prevalence assessment of Aceruloplasminemia using population data.EBioMedicine · 2025Article
- Cryofibrinogen-associated glomerulonephritis with paraproteinemia.Frontiers in immunology · 2025Article
- Implications of the c.1201C > G (p.Arg401Gly) mutation inFrontiers in medicine · 2025Article
- [Congenital dysfibrinogenemia: current status and challenges in diagnosis and treatment].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2024Review
- Congenital fibrinogen disorders: a retrospective clinical and genetic analysis of the Prospective Rare Bleeding Disorders Database.Blood advances · 2024Article
- Article
- Fibrinogen A Alpha-Chain Amyloidosis in Two Chinese Patients.Frontiers in medicine · 2022Article
- Disorders of Fibrinogen and Fibrinolysis.Hematology/oncology clinics of North America · 2021Review
- Congenital Afibrinogenemia and Hypofibrinogenemia: Laboratory and Genetic Testing in Rare Bleeding Disorders with Life-Threatening Clinical Manifestations and Challenging Management.Diagnostics (Basel, Switzerland) · 2021Review
- A novel fibrinogen γ-chain frameshift mutation, p. Cys365Phefs*41, causing hypofibrinogenemia with bleeding phenotype in a Chinese family.Annals of translational medicine · 2021Article
- Hereditary Hypofibrinogenemia with Hepatic Storage.International journal of molecular sciences · 2020Review
- Genetic Variants in theInternational journal of molecular sciences · 2020Review
- Comparison of clinical phenotype with genetic and laboratory results in 31 patients with congenital dysfibrinogenemia in northern Slovakia.International journal of hematology · 2020Article
- Profiling the mutational landscape of coagulation factor V deficiency.Haematologica · 2020Article
- Hepatic fibrinogen storage disease and hypofibrinogenemia caused by fibrinogen Aguadilla mutation: a case report.The Journal of international medical research · 2020Article
- Fibrin(ogen) in human disease: both friend and foe.Haematologica · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibrinogen is a highly pleiotropic protein that is involved in the final step of the coagulation cascade, wound healing, inflammation, and angiogenesis. Heterozygous mutations in Aα, Bβ, or γ fibrinogen-chain genes (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.