Evidence map›Paper›PMID 29239889›Full record

ArticleAIDS (London, England)2018

Are trajectories of a syndemic index in adolescence linked to HIV vulnerability in emerging and young adulthood?

David Córdova, Justin E Heinze, Hsing-Fang Hsieh, Ritesh Mistry, Christopher P Salas-Wright, Stephanie H Cook, Marc A Zimmerman

Abstract read
In one paragraph

Article in AIDS (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David CórdovaSchool of Social Work.
Justin E HeinzeDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Hsing-Fang HsiehDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Ritesh MistryDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan.
Christopher P Salas-WrightSchool of Social Work, Boston University, Boston, Massachusetts.
Stephanie H CookDepartment of Biostatistics and Social and Behavioral Sciences, College of Global Public Health, New York University, New York, New York, USA.
Marc A ZimmermanDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan.

Funding

Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
LONGITUDINAL STUDY OF SCHOOL DROPOUT AND SUBSTANCE USER01DA007484 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZIMMERMAN, MARC A · 1994 to 2011
$5.1M
Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
Preventing HIV/STI in Urban Adolescents via an mHealth Primary Care InterventionR03DA041891 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CORDOVA, DAVID · 2017 to 2018
$311k
NICHD NIH HHS R25 HD045810NIDA NIH HHS R01 DA007484NIDA NIH HHS R03 DA041891NIMHD NIH HHS L60 MD006269NIMH NIH HHS R25 MH067127
6 · The paper itself

Abstract

objectivesTo examine trajectories of adolescent psychosocial risk - drug use, depressive and anxiety symptoms, and violence victimization and observation - and the longitudinal relationship between psychosocial risk trajectories during adolescence and HIV risk behaviors in adulthood.

methodsThe 18-year longitudinal study was conducted from September 1994 through May 2013, in Michigan. Eight hundred and fifty predominantly (80%) African-American adolescents completed demographics and measures of drug use, depressive and anxiety symptoms, violence victimization and observation at Times 1-4, sexual risk behaviors at Times 5 and 6, and social conditions (i.e. family, peer, and community-level factors) between 14.9 and 32.0 years of age.

resultsGrowth mixture modeling revealed two trajectories of psychosocial risk factors which can be characterized as a syndemic index: high-frequency and low-frequency. The high-frequency class was more likely to report HIV risk behaviors, including condomless sex at last sexual intercourse with their primary and secondary partner, sexual intercourse with someone they just met, at least four sexual partners, and licit and illicit drug use prior to sexual intercourse at Time 5 (mean age 23.1). At Time 6 (mean age 32.0), the high-frequency class was more likely to report sexual intercourse with someone they just met and at least four sexual partners, relative to the low-frequency class. In addition, the high-frequency class was linked to peer and family-level indicators of social conditions.

conclusionA syndemic index comprised of co-occurring psychosocial risk factors in adolescence seem to have lasting effects on the vulnerability to engage in HIV risk behaviors in emerging adulthood, some of which extend into young adulthood.

Indexed as

Risk-TakingSyndemicAdolescentAdultAnxietyDepressionFemaleHIV InfectionsHumansLongitudinal StudiesMaleMichiganRisk FactorsSexual BehaviorSubstance-Related DisordersViolence

Identifiers

PMID29239889
PMCPMC5790600

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.