ArticleJournal of neurotrauma2018
A Community Perspective on Bowel Management and Quality of Life after Spinal Cord Injury: The Influence of Autonomic Dysreflexia.
Article in Journal of neurotrauma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Bowel burdens: a systematic review and meta-analysis examining the relationships between bowel dysfunction and quality of life after spinal cord injury.Spinal cord · 2024Pooled it
- Guideline
- Management of Neurogenic Bowel Dysfunction in Adults after Spinal Cord Injury: Clinical Practice Guideline for Health Care Providers.Topics in spinal cord injury rehabilitationGuideline
- Trial
- Article
- Improving TNASCI: addressing classification accuracy, autonomic function, and psychological well-being in SCI.Spinal cord · 2026Article
- Spinal cord neuromodulation for autonomic recovery following spinal cord injury: a scoping review.Journal of neuroengineering and rehabilitation · 2026Article
- Evaluation of bowel management efficacy and subjects' satisfaction in people with spinal cord injury (SCI): An Italian multicenter survey via the MENTOR tool.The journal of spinal cord medicine · 2026Observational
- Article
- Functional improvements correlate with enhanced quality of life following mesenchymal stromal cell therapy in chronic spinal cord injury.Scientific reports · 2025Article
- Dysreflexic dilemma: do we need a revised definition for autonomic dysreflexia?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- On-Line Survey About Autonomic Dysreflexia in Individuals with Spinal Cord Injury in Croatia.Journal of clinical medicine · 2025Article
- Article
- Assessing the feasibility of a bowel management program for patients with neurogenic bowel function after spinal cord injury.Frontiers in medicine · 2025Article
- Autonomic Dysreflexia in Spinal Cord Injury: Mechanisms and Prospective Therapeutic Targets.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024Review
- Rapid-Onset, Short-Duration Induction of Colorectal Contractions in Anesthetized, Adult, Male Rats.The Journal of pharmacology and experimental therapeutics · 2024Article
- Dual-directional regulation of spinal cord injury and the gut microbiota.Neural regeneration research · 2024Review
- Autonomic dysreflexia in urological practice: pathophysiology, prevention and treatment considerations.World journal of urology · 2024Review
- From Toxin to Treatment: A Narrative Review on the Use of Botulinum Toxin for Autonomic Dysfunction.Toxins · 2024Review
- A Literature Review of Nutrition Knowledge Measurement Items Used in Persons Living with Spinal Cord Injuries and Disorders.Topics in spinal cord injury rehabilitation · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autonomic dysfunction is common in individuals with spinal cord injury (SCI) and leads to numerous abnormalities, including profound cardiovascular and bowel dysfunction. In those with high-level lesions, bowel management is a common trigger for autonomic dysreflexia (AD; hypertension provoked by sensory stimuli below the injury level). Improving bowel care is integral for enhancing quality of life (QoL). We aimed to describe the relationships between bowel care, AD, and QoL in individuals with SCI. We performed an online community survey of individuals with SCI. Those with injury at or above T7 were considered at risk for AD. Responses were received from 287 individuals with SCI (injury levels C1-sacral and average duration of injury 17.1 ± 12.9 [standard deviation] years). Survey completion rate was 73% (n = 210). Bowel management was a problem for 78%: it interfered with personal relationships (60%) and prevented staying (62%) and working (41%) away from home. The normal bowel care duration was >60 min in 24% and most used digital rectal stimulation (59%); 33% reported bowel incontinence at least monthly. Of those at risk for AD (n = 163), 74% had AD symptoms during bowel care; 32% described palpitations. AD interfered with activities of daily living in 51%. Longer durations of bowel care (p < 0.001) and more severe AD (p = 0.04) were associated with lower QoL. Bowel management is a key concern for individuals with SCI and is commonly associated with symptoms of AD. Further studies should explore ways to manage bowel dysfunction, increase self-efficacy, and ameliorate the impact of AD to improve QoL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.