Evidence map›Paper›PMID 29239214›Full record

ArticleCNS oncology2018

Brainstem metastases treated with Gamma Knife stereotactic radiosurgery: the Indiana University Health experience.

Ajay Patel, Homan Mohammadi, Tuo Dong, Kevin Ren-Yeh Shiue, Douglas Frye, Yi Le, Shaheryar Ansari, Gordon A Watson, James C Miller, Tim Lautenschlaeger

Abstract read
In one paragraph

Article in CNS oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ajay PatelIndiana University School of Medicine, Indianapolis, IN 46202, USA.
Homan MohammadiIndiana University School of Medicine, Indianapolis, IN 46202, USA.
Tuo DongIndiana University School of Medicine, Indianapolis, IN 46202, USA.
Kevin Ren-Yeh ShiueIndiana University School of Medicine, Indianapolis, IN 46202, USA.
Douglas FryeDepartment of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Yi LeDepartment of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Shaheryar AnsariIndiana University School of Medicine, Indianapolis, IN 46202, USA.
Gordon A WatsonDepartment of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
James C MillerGoodman Campbell Brain & Spine & Department of Neurological Surgery, Indiana University, Indianapolis, IN 46202, USA.
Tim LautenschlaegerDepartment of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brainstem metastases offer a unique challenge in cancer treatment, yet stereotactic radiosurgery (SRS) has proven to be an effective modality in treating these tumors. This report discusses the clinical outcomes of patients with brainstem metastases treated at Indiana University with Gamma Knife (GK) radiosurgery from 2008 to 2016. 19 brainstem metastases from 14 patients who had follow-up brain imaging were identified. Median tumor volume was 0.04 cc (range: 0.01-2.0 cc). Median prescribed dose was 17.5 Gy to the 50% isodose line (range: 14-22 Gy). Median survival after GK SRS treatment to brainstem lesion was 17.2 months (range: 2.8-45.6 months). The experience at Indiana University confirms the safety and efficacy of range of GK SRS prescription doses (14-22 Gy) to brainstem metastases.

Indexed as

RadiosurgeryAcademic Medical CentersAdultAgedBrain NeoplasmsFemaleFollow-Up StudiesHumansIndianaMagnetic Resonance ImagingMaleMiddle AgedRadiotherapy DosageSurvival AnalysisTreatment OutcomeTumor BurdenbrainstemGamma Knifemetastasisradiosurgery

Identifiers

PMID29239214
PMCPMC6001560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.