Evidence map›Paper›PMID 29239132›Full record

ReviewCPT: pharmacometrics & systems pharmacology2018

Translational Systems Pharmacology Studies in Pregnant Women.

Sara K Quinney, Rakesh Gullapelli, David M Haas

Open access · goldAbstract readReview
In one paragraph

Review in CPT: pharmacometrics & systems pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Vancomycin Pharmacokinetics in a Pregnancy Rat Model.Antimicrobial agents and chemotherapy · 2022
    Article
  3. Exploring the Mechanism of Icariin in Osteoporosis Based on a Network Pharmacology Strategy.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  4. Reverse Translational Pharmacology Research Is Driven by Big Data.CPT: pharmacometrics & systems pharmacology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Sara K QuinneyDepartment of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Rakesh GullapelliSchool of Informatics and Computing, Indiana University Purdue University Indianapolis, Indianapolis, Indiana, USA.
David M HaasDepartment of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Indiana University – Purdue University Indianapolis · USIndiana University School of MedicineUniversity of Indianapolis · US

Funding

Individualization of nifedipine dosing for preterm laborK23HD071134 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI QUINNEY, SARA K · 2012 to 2016
$629k
6 · The paper itself

Abstract

Pregnancy involves rapid physiological adaptation and complex interplay between mother and fetus. New analytic technologies provide large amounts of genomic, proteomic, and metabolomics data. The integration of these data through bioinformatics, statistical, and systems pharmacology techniques can improve our understanding of the mechanisms of normal maternal physiologic changes and fetal development. New insights into the mechanisms of pregnancy-related disorders, such as preterm birth (PTB), may lead to the development of new therapeutic interventions and novel biomarkers.

Indexed as

PharmacologyComputational BiologyFemaleGenomicsHumansMetabolomicsPregnancyPregnancy ComplicationsProteomicsTranslational Research, Biomedical

Identifiers

PMID29239132
PMCPMC5824114
OpenAlexW2775032376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.