ArticleZoonoses and public health2018
Zoonotic origin and transmission of Middle East respiratory syndrome coronavirus in the UAE.
Article in Zoonoses and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04420260 (Scheme of Primary Prevention of Infection by COVID-19, in Workers), which is not on this map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Scheme of Primary Prevention of Infection by COVID-19, in Workers: Phase II Controlled Clinical Trial, to be Carried Out in Medellín-Antioquia
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of MERS-CoV seroprevalence and RNA prevalence in dromedary camels: Implications for animal vaccination.Epidemics · 2019Pooled it
- A multi-epitope pan-betacoronavirus vaccine construct predicted to induce broad-spectrum and durable immune responses: an immunoinformatics approach.Frontiers in bioinformatics · 2026Article
- Middle East Respiratory Syndrome Coronavirus Could be a Priority Pathogen to Cause Public Health Emergency: Noticeable Features and Counteractive Measures.Environmental health insights · 2024Article
- Article
- An Overview on the Zoonotic Aspects of COVID-19.Proceedings of the National Academy of Sciences, India. Section B · 2023Review
- Zoonotic diseases transmitted from the camels.Frontiers in veterinary science · 2023Review
- Interrogating the lack of diversity of thought in the pandemic response that led to mistakes - holistic evidence-based approach to deal with future pandemics.Frontiers in public health · 2023Article
- Isolation and genetic characterization of MERS-CoV from dromedary camels in the United Arab Emirates.Frontiers in veterinary science · 2023Article
- Lectins Are the Sparkle of Hope for Combating Coronaviruses and the Global COVID-19.Advanced pharmaceutical bulletin · 2022Review
- Current challenges in different approaches to control COVID-19: a comprehensive review.Bulletin of the National Research Centre · 2022Review
- Global research trends in MERS-CoV: A comprehensive bibliometric analysis from 2012 to 2021.Frontiers in public health · 2022Article
- Bushmeat, wet markets, and the risks of pandemics: Exploring the nexus through systematic review of scientific disclosures.Environmental science & policy · 2021Review
- Review
- Natural product remedies for COVID-19: A focus on safety.South African journal of botany : official journal of the South African Association of Botanists = Suid-Afrikaanse tydskrif vir plantkunde : amptelike tydskrif van die Suid-Afrikaanse Genootskap van Plantkundiges · 2021Review
- The COVID-19 pandemic face mask waste: A blooming threat to the marine environment.Chemosphere · 2021Review
- Machine learning methods accurately predict host specificity of coronaviruses based on spike sequences alone.Biochemical and biophysical research communications · 2020Article
- Review
- Coronaviruses - Potential human threat from foodborne transmission?Lebensmittel-Wissenschaft + [i.e. und] Technologie. Food science + technology. Science + technologie alimentaire · 2020Review
- Coronaviruses disease 2019 (COVID-19): Causative agent, mental health concerns, and potential management options.Journal of infection and public health · 2020Review
- 2019-nCoV: a worldwide concern and facts.Virusdisease · 2020Review
Corrections and comments
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Authors and funding
29 authors.
Funding
Abstract
Since the emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, there have been a number of clusters of human-to-human transmission. These cases of human-to-human transmission involve close contact and have occurred primarily in healthcare settings, and they are suspected to result from repeated zoonotic introductions. In this study, we sequenced whole MERS-CoV genomes directly from respiratory samples collected from 23 confirmed MERS cases in the United Arab Emirates (UAE). These samples included cases from three nosocomial and three household clusters. The sequences were analysed for changes and relatedness with regard to the collected epidemiological data and other available MERS-CoV genomic data. Sequence analysis supports the epidemiological data within the clusters, and further, suggests that these clusters emerged independently. To understand how and when these clusters emerged, respiratory samples were taken from dromedary camels, a known host of MERS-CoV, in the same geographic regions as the human clusters. Middle East respiratory syndrome coronavirus genomes from six virus-positive animals were sequenced, and these genomes were nearly identical to those found in human patients from corresponding regions. These data demonstrate a genetic link for each of these clusters to a camel and support the hypothesis that human MERS-CoV diversity results from multiple zoonotic introductions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.