ArticleJACC. Clinical electrophysiology2017
Spatiotemporal Progression of Early Human Ventricular Fibrillation.
Article in JACC. Clinical electrophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Termination of figure-of-eight reentry via resonant feedback pacing.Frontiers in network physiology · 2025Article
- Distinct spectral dynamics of implanted cardiac defibrillator signals in spontaneous termination of polymorphic ventricular tachycardia and fibrillation in patients with electrical and structural diseases.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022Article
- Electrical Substrate Ablation for Refractory Ventricular Fibrillation: Results of the AVATAR Study.Circulation. Arrhythmia and electrophysiology · 2021Article
- In vivo ratiometric optical mapping enables high-resolution cardiac electrophysiology in pig models.Cardiovascular research · 2019Article
- Interventricular Differences in Action Potential Duration Restitution Contribute to Dissimilar Ventricular Rhythms inFrontiers in cardiovascular medicine · 2019Article
- Analytical approaches for myocardial fibrillation signals.Computers in biology and medicine · 2018Review
- Successful ventricular fibrillation functional substrate ablation via a single vascular access site.HeartRhythm case reports · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Objectives: The objective of this study was to evaluate the spatio-temporal organization and progression of human ventricular fibrillation (VF) in the left (LV) and right (RV) ventricles. Background: Studies suggest that localized sources contribute to VF maintenance, but the evolution of VF episodes has not been quantified. Methods: Synchrony between electrograms recorded from 25 patients with induced VF is computed and used to define the Asynchronous Index (ASI), indicating regions which are out-of-step with surrounding tissue. Computer simulations show that ASI can identify the location of VF-maintaining sources, where larger values of ASI Results: Automated synchrony analysis shows elevated values of ASI in a majority of self-terminating episodes (LV: 8/9, RV: 7/8) and sustained episodes (LV: 11/11, RV: 12/12). The locations of ASI Conclusions: Quantitative analysis identifies localized asynchronous regions that correlate with sources in VF, with sustained episodes evolving to exhibit more stable activation in the LV. This successive increase in stability indicates a stabilizing agent may be responsible for perpetuating fibrillation in a "migrate-and-capture" mechanism in the LV.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.