ArticleJournal of diabetes research2017
Interaction of Pubertal Development and Metabolic Control in Adolescents with Type 1 Diabetes Mellitus.
Article in Journal of diabetes research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Trial
- Sex matters: mechanistic insights into sex-driven patterns of autoimmunity and implications for pharmacotherapy.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Glycemic Control and Adult Height: A Nationwide Swedish Cohort Study on Childhood Type 1 Diabetes.The Journal of clinical endocrinology and metabolism · 2025Article
- Parental Attitude Toward the Engagement in Physical Activity of Their Children with Type 1 Diabetes Mellitus in Hungary.Children (Basel, Switzerland) · 2025Article
- Glycemic control and study of lipid and bone metabolism in type 1 diabetic childrenBiomedica : revista del Instituto Nacional de Salud · 2024Article
- Insulin-like growth factor 1 and sex hormones for assessment of anthropometric and pubertal growth of Egyptian children and adolescents with type 1 diabetes mellitus (single center study).BMC endocrine disorders · 2024Article
- Review
- The Role of Exercise on Cardiometabolic Profile and Body Composition in Youth with Type 1 Diabetes.Children (Basel, Switzerland) · 2022Article
- ISPAD Clinical Practice Consensus Guidelines 2022: Diabetes in adolescence.Pediatric diabetes · 2022Review
- Three-variate trajectories of metabolic control, body mass index, and insulin dose: Heterogeneous response to initiation of pump therapy in youth with type 1 diabetes.Pediatric diabetes · 2022Article
- Effect of the COVID-19 quarantine on metabolic control in children and adolescents with type 1 diabetes.Endocrinologia, diabetes y nutricion · 2022Article
- Serum iron is negatively correlated with the HbA1c level in children and adolescents with type 1 diabetes mellitus.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2022Article
- Psychological State of Camp Counselors with Type 1 Diabetes who Have Attended Diabetes Camp.Kansas journal of medicine · 2022Article
- Effect of the COVID-19 quarantine on metabolic control in children and adolescents with type 1 diabetes.Endocrinologia, diabetes y nutricion · 2021Article
- Continuous glucose monitoring reduces pubertal hyperglycemia of type 1 diabetes.Journal of pediatric endocrinology & metabolism : JPEM · 2020Article
- Potential association between type 1 diabetes mellitus and gender dysphoria.Pediatric diabetes · 2020Observational
- Linear Growth in Children and Adolescents with Type 1 Diabetes Mellitus.International journal of environmental research and public health · 2019Review
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn T1DM, delayed pubertal development and reduced final height are associated with inadequate metabolic control.
objectiveTo assess whether T1DM affects pubertal growth spurt and whether metabolic control during puberty is gender-related.
methodsUsing a large multicentre database, longitudinal data from 1294 patients were analysed. Inclusion criteria: complete records of height and HbA1c from the age of seven to 16 years. Exclusion criteria: other significant chronic diseases and medications, T1DM duration less than three months, and initial BMI < 3rd or >97th percentile.
resultsGrowth velocity (GV) was impaired with a significant reduction of peak GV by 1.2 cm in boys. HbA1c increase during male puberty was lower except for a period of 1.5 years. The highest HbA1c increase in boys coincided with maximum growth spurt. In girls, the highest HbA1c increase was observed during late puberty. Even though there is impaired GV, both sexes reach a height at 16 years of age which corresponds to the background population height.
conclusionWorsening of metabolic control is sex-discordant and associated with gender-specific alterations of GV. However, the vast majority of boys and girls with T1DM seems to reach normal height at the age of 16 years.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.