ArticleJournal of drug and alcohol research2016
CART Peptides and Drugs of Abuse: A Review of Recent Progress.
Article in Journal of drug and alcohol research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Chronic alcohol consumption downregulates TRPA1 ion channel and the main peptidergic messengers of the Edinger-Westphal nucleus.Scientific reports · 2025Article
- Epigenetic editing of Cartpt promotes acquisition and extinction of cocaine memory.bioRxiv : the preprint server for biology · 2025Article
- Striatal transcriptomic alterations immediately after short-term abstinence from methamphetamine self-administration in rats.Molecular brain · 2025Article
- The brainstem reticular formation pivots abnormal neural transmission in the course of Anorexia Nervosa.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Orphan peptide and G protein-coupled receptor signalling in alcohol use disorder.British journal of pharmacology · 2024Review
- Low Dopamine D2 Receptor Expression Drives Gene Networks Related to GABA, cAMP, Growth and Neuroinflammation in Striatal Indirect Pathway Neurons.Biological psychiatry global open science · 2023Article
- Nutritional status and eating habits of people who use drugs and/or are undergoing treatment for recovery: a narrative review.Nutrition reviews · 2021Review
- AddictGene: An integrated knowledge base for differentially expressed genes associated with addictive substance.Computational and structural biotechnology journal · 2021Article
- Feeding the addiction: Narrowing of goals to habits.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2021Article
- Commentary: GPR160 De-Orphanization Reveals Critical Roles in Neuropathic Pain in Rodents (Finally, a Receptor for CART Peptide).Advances in drug and alcohol research · 2021Article
- Molecular changes in the nucleus accumbens and prefrontal cortex associated with the locomotor sensitization induced by coca paste seized samples.Psychopharmacology · 2020Article
- Article
- CART peptide in the nucleus accumbens regulates psychostimulants: Correlations between psychostimulant and CART peptide effects.Neuroscience · 2017Article
- CART Peptide Regulates Psychostimulant-Induced Activity and Exhibits a Rate Dependency.Journal of drug and alcohol research · 2017Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Earlier studies suggesting an involvement of cocaine and amphetamine regulated transcript peptide (CARTp) in the actions of drugs of abuse are confirmed in the most recent publications. This seems especially true for the psychostimulants where CARTp in the nucleus accumbens inhibits or regulates the actions of these drugs; the regulation is lost after repeated drug use which may be an important mechanism in addiction. The other drugs, including nicotine, alcohol, opiates, and perhaps caffeine can affect CARTp or CART mRNA levels. While the exact mechanism is not always clear, the hope is that these findings may provide some insight for the development of medications. While binding studies indicate the existence of specific G-protein coupled receptors (GPCR) receptors for CARTp, major work to be done is the cloning of these receptors.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.