Evidence map›Paper›PMID 29238619›Full record

ArticleNeural plasticity2017

Hippocampal Regulation of Postsynaptic Density Homer1 by Associative Learning.

Nicholas E Clifton, Darren Cameron, Simon Trent, Lucy H Sykes, Kerrie L Thomas, Jeremy Hall

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 44 citations in OpenAlex.

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  16. The Effects of Antipsychotics on the Synaptic Plasticity GeneInternational journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nicholas E CliftonNeuroscience and Mental Health Research Institute, Cardiff University, Cardiff CF24 4HQ, UK.ORCID 0000-0003-2597-5253
Darren CameronMRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff CF24 4HQ, UK.ORCID 0000-0001-7520-7741
Simon TrentNeuroscience and Mental Health Research Institute, Cardiff University, Cardiff CF24 4HQ, UK.
Lucy H SykesNeuroscience and Mental Health Research Institute, Cardiff University, Cardiff CF24 4HQ, UK.
Kerrie L ThomasNeuroscience and Mental Health Research Institute, Cardiff University, Cardiff CF24 4HQ, UK.
Jeremy HallNeuroscience and Mental Health Research Institute, Cardiff University, Cardiff CF24 4HQ, UK.
Cardiff University · GB

Funding

Medical Research Council MR/L010305/1
6 · The paper itself

Abstract

Genes involved in synaptic plasticity, particularly genes encoding postsynaptic density proteins, have been recurrently linked to psychiatric disorders including schizophrenia and autism. Postsynaptic density Homer1 proteins contribute to synaptic plasticity through the competing actions of short and long isoforms. The activity-induced expression of short

Indexed as

AnimalsAssociation LearningBehavior, AnimalConditioning, ClassicalFearHippocampusHomer Scaffolding ProteinsMaleNeuronsRatsAnia-3 protein, ratHomer1 protein, ratHomer Scaffolding Proteins

Identifiers

PMID29238619
PMCPMC5697134
OpenAlexW2765664592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.