Evidence map›Paper›PMID 29238569›Full record

ArticleExtreme physiology & medicine2017

Transient cardiac dysfunction but elevated cardiac and kidney biomarkers 24 h following an ultra-distance running event in Mexican Tarahumara.

Dirk L Christensen, Diana Espino, Rocío Infante-Ramírez, Mónica S Cervantes-Borunda, Rosa P Hernández-Torres, Antonio E Rivera-Cisneros, Daniel Castillo, Kate Westgate, Dijana Terzic, Soren Brage and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Extreme physiology & medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Dirk L ChristensenGlobal Health Section, University of Copenhagen, Øster Farimagsgade 5, building 9, 1014 Copenhagen K, Denmark.
Diana EspinoFaculty of Physical Education and Sport Sciences, Autonomous University of Chihuahua, Chihuahua, Mexico.
Rocío Infante-RamírezFaculty of Chemical Sciences, Autonomous University of Chihuahua, Chihuahua, Mexico.
Mónica S Cervantes-BorundaFaculty of Nursing and Nutrition, Autonomous University of Chihuahua, Chihuahua, Mexico.
Rosa P Hernández-TorresFaculty of Nursing and Nutrition, Autonomous University of Chihuahua, Chihuahua, Mexico.
Antonio E Rivera-CisnerosFaculty of Medicine, Autonomous University of Guadalajara, Jalisco, Mexico.
Daniel CastilloFaculty of Medicine, Autonomous University of Chihuahua, Chihuahua, Mexico.
Kate WestgateGlobal Health Section, University of Copenhagen, Øster Farimagsgade 5, building 9, 1014 Copenhagen K, Denmark.
Dijana TerzicDepartment of Clinical Biochemistry, Centre of Diagnostics, Copenhagen University Hospital, Rigshospitalet, Denmark.
Soren BrageGlobal Health Section, University of Copenhagen, Øster Farimagsgade 5, building 9, 1014 Copenhagen K, Denmark.
Christian HassagerDepartment of Cardiology, Heart Centre, Copenhagen University Hospital, Rigshospitalet, Denmark.
Jens P GoetzeDepartment of Clinical Biochemistry, Centre of Diagnostics, Copenhagen University Hospital, Rigshospitalet, Denmark.
Jesper KjaergaardDepartment of Cardiology, Heart Centre, Copenhagen University Hospital, Rigshospitalet, Denmark.
Autonomous University of Chihuahua · MXCopenhagen University Hospital · DKUniversity of Copenhagen · DKRigshospitalet · DKUniversidad de Guadalajara · MXUniversity of Cambridge · GB

Funding

Medical Research Council MC_UU_12015/3
6 · The paper itself

Abstract

backgroundThe Mexican Tarahumara are accustomed to running ultra-distance races. No data exist on the acute physiological changes following ultra-distance running and physiological-biomarker associations in this population. Thus, we aimed to investigate the acute impact (≤ 24 h) on functional and biochemical changes of the cardiac muscle and biochemical changes associated with kidney function following a 63-km ultra-distance race with an altitude difference of 1800 m in Mexican Tarahumara athletes.

methodsTen Tarahumara male athletes (mean ± SD age = 29.9 ± 6.6 years) volunteered to participate in the study. VO

resultsEstimated mean VO

conclusionsThe athletes participating in this study had acute transient cardiac dysfunction as assessed by echocardiography but elevated cardiac and kidney biomarkers at 24 h following a 63-km race with extreme altitude variation.

Indexed as

Cardiac biomarkersEchocardiographyKidney biomarkersTarahumaraUltra-marathon

Identifiers

PMID29238569
PMCPMC5725886
OpenAlexW2771224695

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.