ArticleIranian journal of basic medical sciences2017
Vitamin E improved bone strength and bone minerals in male rats given alcohol.
Article in Iranian journal of basic medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Metabolic and Redox-Related Effects of Mauritia flexuosa (Buriti) Oil Supplementation in Wistar Rats.Journal of food science · 2026Article
- Vitamins C and E alleviate the deleterious effects of electronic cigarettes on tongue muscles and nerves in rat model.BMC oral health · 2025Article
- Vitamin E Improves Cellular and Structural Bone Histomorphometry in an Alcohol-Induced Osteoporosis Rat Model.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Article
- The Effect of Intra-socket Vitamin E Application on the Reduction in Postoperative Pain and Reduction in Incidence of Dry Socket in Female Patients: A Randomized Controlled Trial.Journal of maxillofacial and oral surgery · 2024Article
- Administration of alpha-lipoic acid could maintain bone mass and bone strength in senile female rats with alcohol consumption.Zeitschrift fur Gerontologie und Geriatrie · 2020Article
- Resveratrol reverses the negative effect of alcohol on hydroxyapatite-coated implant osseointegration in senile female rats.Zeitschrift fur Gerontologie und Geriatrie · 2020Article
- Determinants of Bone Health Status in a Multi-Ethnic Population in Klang Valley, Malaysia.International journal of environmental research and public health · 2020Article
- Combined virgin coconut oil and tocotrienol-rich fraction protects against bone loss in osteoporotic rat model.Veterinary world · 2019Article
- The Molecular Mechanism of Vitamin E as a Bone-Protecting Agent: A Review on Current Evidence.International journal of molecular sciences · 2019Review
- The Role of Tocotrienol in Preventing Male Osteoporosis-A Review of Current Evidence.International journal of molecular sciences · 2019Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAlcohol consumption induces oxidative stress on bone, which in turn increases the risk of osteoporosis. This study determined the effects of vitamin E on bone strength and bone mineral content in alcohol-induced osteoporotic rats. MATERIALS AND
methodsThree months old Sprague Dawley male rats were randomly divided into 5 groups: (I) control group; (II) alcohol (3g/kg) + normal saline; (III) alcohol (3g/kg) + olive oil; (IV) alcohol (3g/kg) + alpha-tocopherol (60mg/kg) and (V) alcohol (3g/kg) + palm vitamin E (60mg/kg). The treatment lasted for three months. Following sacrifice, the right tibia was subjected to bone biomechanical test while the lumbar (fourth and fifth lumbar) and left tibia bones were harvested for bone mineral measurement.
resultsAlcohol caused reduction in bone biomechanical parameters (maximum force, ultimate stress, yield stress and Young's modulus) and bone minerals (bone calcium and magnesium) compared to control group (
conclusionBoth palm vitamin E and alpha-tocopherol improved bone mineral content which was reduced by alcohol. However, only palm vitamin E was able to improve bone strength in alcohol treated rats.
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