Evidence map›Paper›PMID 29238338›Full record

ArticleFrontiers in microbiology2017

A Novel TetR Family Transcriptional Regulator, CalR3, Negatively Controls Calcimycin Biosynthesis in

Lixia Gou, Tiesheng Han, Xiaoxia Wang, Jingxuan Ge, Wenxiu Liu, Fen Hu, Zhijun Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Metabolic engineering ofEngineering microbiology · 2022
    Review
  12. Article
  13. Article
  14. The regulatory cascades of antibiotic production in Streptomyces.World journal of microbiology & biotechnology · 2020
    Review
  15. The Application of Regulatory Cascades inFrontiers in microbiology · 2020
    Review
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lixia GouSchool of Life Sciences, North China University of Science and Technology, Tangshan, China.
Tiesheng HanSchool of Life Sciences, North China University of Science and Technology, Tangshan, China.
Xiaoxia WangSchool of Life Sciences, North China University of Science and Technology, Tangshan, China.
Jingxuan GeSchool of Life Sciences, North China University of Science and Technology, Tangshan, China.
Wenxiu LiuSchool of Life Sciences, North China University of Science and Technology, Tangshan, China.
Fen HuSchool of Life Sciences, North China University of Science and Technology, Tangshan, China.
Zhijun WangState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
North China University of Science and Technology · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcimycin is a unique ionophoric antibiotic that is widely used in biochemical and pharmaceutical applications, but the genetic basis underlying the regulatory mechanisms of calcimycin biosynthesis are unclear. Here, we identified the

Indexed as

biosynthesiscalcimycinCalR3 ligandsStreptomyces chartreusisTetR family regulator

Identifiers

PMID29238338
PMCPMC5712553
OpenAlexW2770395622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.