Evidence map›Paper›PMID 29238188›Full record

ReviewInternational journal of nanomedicine2017

Effects of major parameters of nanoparticles on their physical and chemical properties and recent application of nanodrug delivery system in targeted chemotherapy.

Jing Zhang, Hua Tang, Zefa Liu, Baoan Chen

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Review
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  10. Biomacromolecules · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Recent Advances in Targeted Therapies for Infantile Hemangiomas.International journal of nanomedicine · 2024
    Review
  18. Development of pH-ResponsiveMolecules (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Nano-biotechnology in tumour and cancerous disease: A perspective review.Journal of cellular and molecular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing Zhang *Department of Hematology and Oncology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing.
Hua Tang *Department of Hematology, People's Hospital of Xinghua City, Xinghua City, Jiangsu Province, People's Republic of China.
Zefa LiuDepartment of Hematology, People's Hospital of Xinghua City, Xinghua City, Jiangsu Province, People's Republic of China.
Baoan ChenDepartment of Hematology and Oncology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemotherapy is still one of the main cancer therapy treatments, but the curative effect of chemotherapy is relatively low, as such the development of a new cancer treatment is highly desirable. The gradual maturation of nanotechnology provides an innovative perspective not only for cancer therapy but also for many other applications. There are a diverse variety of nanoparticles available, and choosing the appropriate carriers according to the demand is the key issue. The performance of nanoparticles is affected by many parameters, mainly size, shape, surface charge, and toxicity. Using nanoparticles as the carriers to realize passive targeting and active targeting can improve the efficacy of chemotherapy drugs significantly, reduce the mortality rate of cancer patients, and improve the quality of life of patients. In recent years, there has been extensive research on nanocarriers. In this review, the effects of several major parameters of nanoparticles on their physical and chemical properties are reviewed, and then the recent progress in the application of several commonly used nanoparticles is presented.

Indexed as

Antineoplastic AgentsDendrimersDrug CarriersDrug Delivery SystemsHumansLiposomesMicellesNanoparticlesNanotechnologyNanotubes, CarbonNeoplasmsParticle SizeAntineoplastic AgentsDendrimersDrug CarriersLiposomesMicellesNanotubes, Carbonchemotherapydrug targeting deliverynanocarrierparameters

Identifiers

PMID29238188
PMCPMC5713688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.