Evidence map›Paper›PMID 29238182›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease2017

Adherence to a COPD treatment guideline among patients in Hong Kong.

Ka Pang Chan, Fanny Ws Ko, Hok Sum Chan, Mo Lin Wong, Thomas Yw Mok, Kah Lin Choo, David Sc Hui

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Quality of Care and Outcomes of Inpatients with COPD: A Multi-Center Study in China.International journal of chronic obstructive pulmonary disease · 2025
    Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The Impact of the Pay-for-Performance Program on the Outcome of COPD Patients in Taiwan After One Year.International journal of chronic obstructive pulmonary disease · 2022
    Article
  9. Does Evaluation and Management of COPD Follow Therapeutic Strategy Recommendations?Chronic obstructive pulmonary diseases (Miami, Fla.) · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Compliance of Pharmacotherapy with GOLD Guidelines: A Longitudinal Study in Patients with COPD.International journal of chronic obstructive pulmonary disease · 2020
    Article
  15. Article
  16. Current Status of the Treatment of COPD in China: A Multicenter Prospective Observational Study.International journal of chronic obstructive pulmonary disease · 2020
    Observational
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ka Pang ChanDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital.
Fanny Ws KoDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital.
Hok Sum ChanDepartment of Medicine, Alice Ho Miu Ling Nethersole Hospital.
Mo Lin WongDepartment of Medicine and Geriatrics, Caritas Medical Centre.
Thomas Yw MokRespiratory Medical Department, Kowloon Hospital.
Kah Lin ChooDepartment of Medicine, North District Hospital, Hong Kong.
David Sc HuiDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital.
Prince of Wales Hospital · CNAlice Ho Miu Ling Nethersole Hospital · CNKowloon Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to assess the adherence rate of pharmacological treatment to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline published in 2011 and the prevalence of comorbidities among patients with COPD in Hong Kong (HK).

methodsPatients were recruited from five tertiary respiratory centers and followed up for 12 months. Data on baseline physiological, spirometric parameters, use of COPD medications and coexisting comorbidities were collected. The relationship between guideline adherence rate and subsequent COPD exacerbations was assessed.

resultsAltogether, 450 patients were recruited. The mean age was 73.7±8.5 years, and 92.2% of them were males. Approximately 95% of them were ever-smokers, and the mean post-bronchodilator (BD) forced expiratory volume in 1 second was 50.8%±21.7% predicted. The mean COPD Assessment Test and modified Medical Research Council Dyspnea Scale were 13.2±8.1 and 2.1±1.0, respectively. In all, five (1.1%), 164 (36.4%), eight (1.8%) and 273 (60.7%) patients belonged to COPD groups A, B, C and D, respectively. The guideline adherence rate for pharmacological treatment ranged from 47.7% to 58.1% in the three clinic visits over 12 months, with overprescription of inhaled corticosteroids (ICS) and underutilization of long-acting BDs in group B COPD patients. Guideline nonadherence was not associated with increased risk of exacerbation after adjustment of confounding variables. However, this study was not powered to assess a difference in exacerbations. In all, 80.9% of patients had at least one comorbidity.

conclusionA suboptimal adherence to GOLD guideline 2011, with overprescription of ICS, was identified. The commonly found comorbidities also aligned with the trend observed in other observational cohorts.

Indexed as

Administration, InhalationAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAgedAged, 80 and overBronchodilator AgentsComorbidityDisease ProgressionDrug Therapy, CombinationFemaleForced Expiratory VolumeGuideline AdherenceHong KongHumansLungMaleAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsBronchodilator AgentsMuscarinic AntagonistsPhosphodiesterase 4 InhibitorsadherenceCOPDGOLD guideline

Identifiers

PMID29238182
PMCPMC5713700
OpenAlexW2769745405

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.