ArticleSpinal cord2018
Increased psychological distress among individuals with spinal cord injury is associated with central neuropathic pain rather than the injury characteristics.
Article in Spinal cord, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of non-invasive brain-computer interface technology on the therapeutic effect of patients with spinal cord injury: a summary of evidence based on meta-analysis.Journal of neuroengineering and rehabilitation · 2025Pooled it
- The Link Between Exposure to Traumatic Stress and Chronic Pain: The Mediation Effect of Hyperarousal Is Moderated by Sensitivity to Pain Traumatization.European journal of pain (London, England) · 2026Article
- Exposure-based Interventions for Chronic Pain and Bodily Symptoms: A Special Interest Meeting Report.Behaviour research and therapy · 2026Article
- Exploring Pain on Social Media: Observational Study on Perceptions and Discussions of Chronic Pain Conditions.JMIR infodemiology · 2025Observational
- Predicting chronic pain two years following a spinal cord injury: Longitudinal study on the reciprocal role of acute pain and PTSD symptoms.The journal of spinal cord medicine · 2025Article
- Clinical Characteristics of Adults Living with a Spinal Cord Injury Across the Continuum of Care: A Population-Based Cross-Sectional Study.Journal of clinical medicine · 2025Article
- The relationship between changes in inflammation and locomotor function in sensory phenotypes of central neuropathic pain after spinal cord injury.Pain reports · 2024Article
- Emotional burden among MS patients: associations between specific chronic pain diagnoses and psychological features.Journal of neurology · 2024Article
- A Case Study of Hypnosis Enhanced Cognitive Therapy for Pain in a Ventilator Dependent Patient during Inpatient Rehabilitation for Spinal Cord Injury.Journal of clinical medicine · 2023Article
- A preliminary study evaluating self-reported effects of cannabis and cannabinoids on neuropathic pain and pain medication use in people with spinal cord injury.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Non-opioid pharmacologic treatment of chronic spinal cord injury-related pain.The journal of spinal cord medicine · 2022Review
- Association of psychological variants with functional outcomes among people with spinal cord injury.Scientific reports · 2021Observational
- Post-traumatic stress disorder symptoms and pain intensity in persons with spinal cord injury.Spinal cord · 2021Article
- miR-30b Promotes spinal cord sensory function recovery via the Sema3A/NRP-1/PlexinA1/RhoA/ROCK Pathway.Journal of cellular and molecular medicine · 2020Article
- Central Neuropathic Mechanisms in Pain Signaling Pathways: Current Evidence and Recommendations.Advances in therapy · 2020Review
- Metformin: A Prospective Alternative for the Treatment of Chronic Pain.Frontiers in pharmacology · 2020Review
- Correlation between thyroid function, testosterone levels, and depressive symptoms in females with spinal cord injury.Spinal cord series and cases · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designCross-sectional study.
objectivesCentral neuropathic pain (CNP) is common after spinal cord injury (SCI). The psychological impact of CNP is not clear. Previous studies reported depression and pain catastrophizing among patients with SCI and CNP; however, the lack of control groups prevented discerning whether these were attributed to CNP or to the SCI itself. The aim was to examine the psychological distress among individuals with SCI with and without CNP and controls to evaluate its impact and possible source.
settingOutpatient clinic of a large rehabilitation center.
methodsIndividuals with SCI and CNP (n = 27) and without CNP (n = 23), and able-bodied controls (n = 20) participated. Data collection included sociodemographics, SCI characteristics, and level of post-traumatic stress disorder (PTSD), anxiety, stress, depression, and pain catastrophizing. The sensory, affective, and cognitive dimensions of CNP were analyzed.
resultsIndividuals with SCI and CNP exhibited elevated levels of PTSD, anxiety, stress, depression, and pain catastrophizing compared to the two control groups, which presented similar levels. The psychological variables among the CNP group correlated positively only with the affective dimension of CNP. Neither CNP nor the psychological variables correlated with SCI characteristics.
conclusionsIrrespective of CNP intensity, the affective dimension (suffering) is associated with increased psychological distress. Perhaps individual differences in the response to SCI and/or individual traits rather than the mere exposure to SCI may have a role in the emergence of CNP and psychological distress/mood dysfunction. Rehabilitation programs should prioritize stress management and prevention among individuals with SCI and CNP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.