Evidence map›Paper›PMID 29237788›Full record

ArticleJournal of clinical microbiology2018

Nucleic Acid Amplification Test Quantitation as Predictor of Toxin Presence in Clostridium difficile Infection.

M J T Crobach, N Duszenko, E M Terveer, C M Verduin, E J Kuijper

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Evaluation of the Cepheid Xpert C. difficile diagnostic assay: an update meta-analysis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Diagnosis ofJournal of medical microbiology · 2024
    Review
  6. Review
  7. Rapid Quantification ofAnalytical chemistry · 2022
    Article
  8. Significance of a polymerase chain reaction method in the detection of Clostridioides difficile.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Article
  9. Article
  10. Article
  11. Laboratory Tests for the Diagnosis ofClinics in colon and rectal surgery · 2020
    Review
  12. South African Society of Clinical MicrobiologySouthern African journal of infectious diseases · 2020
    Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

M J T Crobach *Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands m.j.t.crobach@lumc.nl.
N Duszenko *Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
E M TerveerDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
C M VerduinDepartment of Microbiology and Infection Prevention, Amphia Hospital, Breda, The Netherlands.
E J KuijperDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands.
Leiden University Medical Center · NLAmphia Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multistep algorithmic testing in which a sensitive nucleic acid amplification test (NAAT) is followed by a specific toxin A and toxin B enzyme immunoassay (EIA) is among the most accurate methods for

Indexed as

AlgorithmsBacterial ProteinsBacterial ToxinsClostridioides difficileClostridium InfectionsDiagnostic Tests, RoutineEnterotoxinsFecesHospitalsHumansImmunoenzyme TechniquesNetherlandsNucleic Acid Amplification TechniquesPredictive Value of TestsRetrospective StudiesROC CurveBacterial ProteinsBacterial ToxinsEnterotoxinstcdA protein, Clostridium difficiletoxB protein, Clostridium difficileClostridium difficilediagnosticNAAT quantitation

Identifiers

PMID29237788
PMCPMC5824036
OpenAlexW2790105101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.