Evidence map›Paper›PMID 29237778›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

mPGES1-Dependent Prostaglandin E

Damian Maseda, Elizabeth M Johnson, Lindsay E Nyhoff, Bridgette Baron, Fumiaki Kojima, Ashley J Wilhelm, Martin R Ward, Jerold G Woodward, David D Brand, Leslie J Crofford

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. A CD4Immunity · 2025
    Article
  3. Article
  4. Microsomal Prostaglandin E Synthase-1 Controls Colonic Prostaglandin EInternational journal of molecular sciences · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Prostaglandin EScience advances · 2021
    Article
  13. Article
  14. Review
  15. The Effect of Lipid Metabolism on CD4Mediators of inflammation · 2021
    Review
  16. Article
  17. Mechanisms of immune evasion in bladder cancer.Cancer immunology, immunotherapy : CII · 2020
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Damian MasedaDivision of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37202.
Elizabeth M JohnsonDivision of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37202.
Lindsay E NyhoffDivision of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37202.
Bridgette BaronDivision of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37202.
Fumiaki KojimaDepartment of Pharmacology, Kitasato University, Tokyo 108-8641, Japan.
Ashley J WilhelmDivision of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37202.
Martin R WardUniversity of Kentucky Medical Center, Lexington, KY 40536; and.
Jerold G WoodwardUniversity of Kentucky Medical Center, Lexington, KY 40536; and.
David D BrandDivision of Rheumatology, University of Tennessee, Memphis, TN 38104.ORCID 0000-0002-9260-7963
Leslie J CroffordDivision of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37202; leslie.j.crofford@vanderbilt.edu.
Vanderbilt University Medical Center · USUniversity of Kentucky · USKitasato University · JPUniversity of Tennessee Health Science Center · US

Funding

Prostaglandin E synthase in rheumatoid arthritisR01AR049010 · NIAMS · VANDERBILT UNIVERSITY · PI CROFFORD, LESLIE J · 2004 to 2014
$2.9M
Elucidating the Mechanisms that link the Shared Epitope, Periodontal Disease and ArthritisI01BX003487 · VA · MEMPHIS VA MEDICAL CENTER · PI BRAND, DAVID D. · 2017 to 2020
–
NIAMS NIH HHS R01 AR049010
6 · The paper itself

Abstract

The integration of inflammatory signals is paramount in controlling the intensity and duration of immune responses. Eicosanoids, particularly PGE

Indexed as

Autocrine CommunicationParacrine CommunicationAnimalsDinoprostoneEpitopes, T-LymphocyteGene Expression RegulationImmunizationImmunomodulationLymphocyte ActivationMicePhenotypeProstaglandin-E SynthasesReceptors, Prostaglandin E, EP2 SubtypeReceptors, Prostaglandin E, EP4 SubtypeTh17 CellsTh1 CellsDinoprostoneEpitopes, T-LymphocyteProstaglandin-E SynthasesPtges protein, mouseReceptors, Prostaglandin E, EP2 SubtypeReceptors, Prostaglandin E, EP4 Subtype

Identifiers

PMID29237778
PMCPMC5760456
OpenAlexW2773826721

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.